4,5-dimethyl-1-(4-nitro-phenyl)-1,6-dihydro-pyridazine | 57103-78-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,5-dimethyl-1-(4-nitro-phenyl)-1,6-dihydro-pyridazine
• 英文别名: 4,5-Dimethyl-1-(4-nitrophenyl)-1,6-dihydropyridazine；4,5-dimethyl-2-(4-nitrophenyl)-3H-pyridazine
• CAS: 57103-78-3
• 化学式: C₁₂H₁₃N₃O₂
• 分子量: 231.254
• InChiKey: VZFLWSDYPCKAOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  61.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (4-nitrophenyl)-piperidin-1-yldiazene 以 乙酸乙酯 、 乙腈 为溶剂， 反应 0.17h， 生成 4,5-dimethyl-1-(4-nitro-phenyl)-1,6-dihydro-pyridazine
  参考文献：
  名称：

  The sequel to a carbocyclic nucleoside synthesis: a divergent access to both arenediazonium ions and aryl triflates

  摘要：

  Depending on the amount of acid used, treating aryl-dialkyl triazenes of general structure 3 with triflic acid resulted in the formation of either the corresponding arenediazonium triflates 4 or aryl triflates 8 apparently by two different pathways, the latter conversion being favoured at high acid concentration. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.01.147

文献信息

• The sequel to a carbocyclic nucleoside synthesis: a divergent access to both arenediazonium ions and aryl triflates
  作者：C Picherit、F Wagner、D Uguen

  DOI：10.1016/j.tetlet.2004.01.147

  日期：2004.3

  Depending on the amount of acid used, treating aryl-dialkyl triazenes of general structure 3 with triflic acid resulted in the formation of either the corresponding arenediazonium triflates 4 or aryl triflates 8 apparently by two different pathways, the latter conversion being favoured at high acid concentration. (C) 2004 Elsevier Ltd. All rights reserved.