Cyclopropyl(3-methylphenyl)methanamine | 535925-72-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cyclopropyl(3-methylphenyl)methanamine
• 英文别名: cyclopropyl-(3-methylphenyl)methanamine
• CAS: 535925-72-5
• 化学式: C₁₁H₁₅N
• 分子量: 161.24
• InChiKey: JCHKGNDBHAFTHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• SULFONYLAMINO-ACETIC ACID DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS
  申请人：Actelion Pharmaceuticals Ltd.

  公开号：EP1554239A2

  公开（公告）日：2005-07-20
• [EN] SULFONYLAMINO-ACETIC ACID DERIVATIVES<br/>[FR] DERIVES D'ACIDE SULFONYLAMINO-ACETIQUE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2004033418A2

  公开（公告）日：2004-04-22

  The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
• [EN] USE OF TETRAHYDROPYRIDINE DERIVATIVES<br/>[FR] UTILISATION DE DERIVES DE TETRAHYDROPYRIDINE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2004105738A2

  公开（公告）日：2004-12-09

  The invention relates to tetrahydropyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of plasmepsin II.