Fetidine | 7072-86-8

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 阿朴菲
• 英文名称: Fetidine
• 英文别名: (6aS)-9-[6-[[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2,3-dimethoxyphenoxy]-2,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol
• CAS: 7072-86-8
• 化学式: C₄₀H₄₆N₂O₈
• 分子量: 682.8
• InChiKey: IBHSRCBKJMEBQB-VMPREFPWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  50
• 可旋转键数：
  10
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  91.3
• 氢给体数：
  1
• 氢受体数：
  10

文献信息

• Topical formulations and methods of use
  申请人：Morariu Marius

  公开号：US20060216251A1

  公开（公告）日：2006-09-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-1-carnitine, and 1-carnosine.

  本发明提供了一种外用组合物，该组合物包含硫辛酸、肉毒碱和肉毒碱，并以适合外用的载体形式存在，还提供了一种治疗皮肤的方法。本组合物有助于改善以皱纹和失去弹性为特征的老化皮肤的外观。优选成分包括 R-硫辛酸或 R-二氢硫辛酸、乙酰基-1-肉碱和 1-肉碱。
• TREATMENT FOR OCULAR INFLAMMATION
  申请人：MASSACHUSETTS EYE & EAR INFIRMARY

  公开号：EP0820286A1

  公开（公告）日：1998-01-28
• TETRANDRINE FOR THE TREATMENT FOR OCULAR INFLAMMATION
  申请人：MASSACHUSETTS EYE & EAR INFIRMARY

  公开号：EP0820286B1

  公开（公告）日：2006-01-04
• EP0820286A4
  申请人：——

  公开号：EP0820286A4

  公开（公告）日：2000-01-05
• Methods of Treating Skin
  申请人：Morariu Marius

  公开号：US20100272790A1

  公开（公告）日：2010-10-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.