苯基甲烷磺酸 | 57267-76-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 苯基甲烷磺酸
• CAS: 57267-76-2
• 化学式: C7H8NaO3S
• 分子量: 195.19
• InChiKey: USVKKJUSLJKPHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.69
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS<br/>[FR] COMPOSES CHIMIQUES
  申请人：GLAXO GROUP LTD

  公开号：WO2002059110A1

  公开（公告）日：2002-08-01

  Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

  本文描述了一种有用的VEGFR2抑制剂嘧啶衍生物。所述的发明还包括制备这种嘧啶衍生物的方法以及在治疗高增殖性疾病中使用它们的方法。
• [EN] PYRIMIDINE COMPOUNDS<br/>[FR] COMPOSES DE PYRIMIDINE
  申请人：SMITHKLINE BEECHAM CORP

  公开号：WO2003066601A1

  公开（公告）日：2003-08-14

  Pyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

  本文描述了用作TIE-2和/或VEGFR-2抑制剂的嘧啶衍生物。所述发明还包括制备这种嘧啶衍生物的方法以及在治疗过度增殖性疾病中使用它们的方法。
• Chemical compounds
  申请人：Boloor Amogh

  公开号：US20070015756A1

  公开（公告）日：2007-01-18

  Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

  本文描述了一种有用于VEGFR2抑制剂的嘧啶衍生物。所述发明还包括制备此类嘧啶衍生物的方法，以及在治疗过度增殖性疾病中使用它们的方法。
• Pyrimidine compounds
  申请人：Cheung Mui

  公开号：US20050085637A1

  公开（公告）日：2005-04-21

  Pyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

  本文介绍了一种作为TIE-2和/或VEGFR-2抑制剂有用的嘧啶衍生物。所述发明还包括制备此类嘧啶衍生物的方法，以及使用它们治疗过度增殖性疾病的方法。
• CHEMICAL COMPOUNDS
  申请人：Brown Lee Matthew

  公开号：US20070142437A1

  公开（公告）日：2007-06-21

  Oxazole derivatives, which are useful as VEGFR2, CDK2, and CDK4 inhibitors are described herein. The described invention also includes methods of making such oxazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

  本文描述了一种有用的噁唑衍生物，可作为VEGFR2、CDK2和CDK4抑制剂。所述发明还包括制备这种噁唑衍生物的方法，以及在治疗高增殖性疾病方面使用它们的方法。