[5-[Dimethyl(2-phenylethynyl)silyl]-1,1-dimethyl-3,4-diphenylsilol-2-yl]-(4-methylphenyl)methanone | 1171854-93-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: [5-[Dimethyl(2-phenylethynyl)silyl]-1,1-dimethyl-3,4-diphenylsilol-2-yl]-(4-methylphenyl)methanone
• 英文别名: [5-[dimethyl(2-phenylethynyl)silyl]-1,1-dimethyl-3,4-diphenylsilol-2-yl]-(4-methylphenyl)methanone
• CAS: 1171854-93-5
• 化学式: C₃₆H₃₄OSi₂
• 分子量: 538.836
• InChiKey: OUPDULZPOIKBRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.72
• 重原子数：
  39
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (1,4-diiodo-2,3-diphenylbuta-1,3-diene-1,4-diyl)bis(dimethyl(phenylethynyl)silane) 、 对甲基苯甲酰氯 在 叔丁基锂 作用下， 以 四氢呋喃 、 正戊烷 为溶剂， 反应 2.5h， 以94%的产率得到[5-[Dimethyl(2-phenylethynyl)silyl]-1,1-dimethyl-3,4-diphenylsilol-2-yl]-(4-methylphenyl)methanone
  参考文献：
  名称：

  Synthesis of functionalized siloles from Si-tethered diynes

  摘要：

  A new synthetic itinerary to silole from Si-tethered diynes is reported. In this protocol, the Si-tethered diyne manifests definitely the reactivity of monoyne to form the lithio silole via zirconacyclopetadiene, 1,4-diiodo-1,3-butadiene, and the corresponding dilithiodiene successively. Lithio siloles thus obtained above could be easily functionalized to give various types of silole derivatives. Complex structure like bridged bis-silole compounds could also be constructed by this process. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.01.152

文献信息

• Synthesis of functionalized siloles from Si-tethered diynes
  作者：Qian Luo、Li Gu、Chao Wang、Junhui Liu、Wenxiong Zhang、Zhenfeng Xi

  DOI：10.1016/j.tetlet.2009.01.152

  日期：2009.7

  A new synthetic itinerary to silole from Si-tethered diynes is reported. In this protocol, the Si-tethered diyne manifests definitely the reactivity of monoyne to form the lithio silole via zirconacyclopetadiene, 1,4-diiodo-1,3-butadiene, and the corresponding dilithiodiene successively. Lithio siloles thus obtained above could be easily functionalized to give various types of silole derivatives. Complex structure like bridged bis-silole compounds could also be constructed by this process. (C) 2009 Elsevier Ltd. All rights reserved.