2-Amino-benzidin | 2835-69-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Amino-benzidin
• 英文别名: biphenyl-2,4,4'-triyltriamine；2.4.4'-Triamino-biphenyl；2.4.4'-Triamino-diphenyl；(1,1'-biphenyl)-2,4,4'-triamine；4'-aminobiphenyl-2,4-diamine；[1,1'-Biphenyl]-2,4,4'-triamine；4-(4-aminophenyl)benzene-1,3-diamine
• CAS: 2835-69-0
• 化学式: C₁₂H₁₃N₃
• mdl: MFCD11053013
• 分子量: 199.255
• InChiKey: GMJHZZCVWDJKFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Amino-benzidin 生成 N,N',N''-biphenyl-2,4,4'-triyl-tris-carbamic acid trimethyl ester
  参考文献：
  名称：

  Siefken, Justus Liebigs Annalen der Chemie, 1949, vol. 562, p. 75,1114

  摘要：

  DOI：
• 作为产物：
  描述：

  2-硝基联苯胺 在 盐酸 、 tin(ll) chloride 作用下， 生成 2-Amino-benzidin
  参考文献：
  名称：

  SOME DERIVATIVES OF BENZIDINE

  摘要：

  DOI：

  10.1246/bcsj.9.150

文献信息

• Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
  申请人：Lim Mu'lll

  公开号：US20060156481A1

  公开（公告）日：2006-07-20

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one N-oxides of six-membered rings with one or two nitrogen atoms keratin dyeing compound. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  氧化染色角蛋白纤维的配方，包括适用于染色的介质和至少一种含有一个或两个氮原子的六元环N-氧化物的角蛋白染料化合物。一种氧化染色角蛋白纤维的方法，包括在氧化剂存在下施用这种配方，以足够时间发展所需的着色。
• [EN] PROCESS FOR THE PREPARATION OF RIDINILAZOLE AND CRYSTALLINE FORMS THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION DE RIDINILAZOLE ET DE FORMES CRISTALLINES DE CELUI-CI
  申请人：SUMMIT OXFORD LTD

  公开号：WO2021009514A1

  公开（公告）日：2021-01-21

  Described are processes for the preparation of 2,2'-di(pyridin-4-yl)-1H,1'H-5,5'- bibenzo[d]imidazole (which may also be known as 5,5'bis-[2-(4-pyridinyl)-1H- benzimidazole]), referenced herein by the INN name ridinilazole, and pharmaceutically acceptable derivatives, salts, hydrates, solvates, complexes, bioisosteres, metabolites or prodrugs thereof. The invention also relates to various compositions of purified ridinilazole, to various crystalline forms of ridinilazole, to processes for their preparation and to related pharmaceutical preparations and uses thereof (including their medical use and their use in the efficient large-scale synthesis of ridinilazole).

  介绍了制备2,2'-二(吡啶-4-基)-1H,1'H-5,5'-双苯并[d]咪唑(也可以被称为5,5'-双-[2-(4-吡啶基)-1H-苯并咪唑])的过程，该化合物在此处以国际非专利药品名称ridinilazole命名，以及其药学上可接受的衍生物、盐、水合物、溶剂化物、配合物、生物等效物、代谢物或前药。本发明还涉及纯化ridinilazole的各种组合物、ridinilazole的各种晶体形式、其制备过程以及相关的制药制剂和用途(包括其医学用途和在ridinilazole的高效大规模合成中的应用)。
• Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof
  申请人：Dahlgren Richard Marc

  公开号：US20090282622A1

  公开（公告）日：2009-11-19

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one 3-substituted pyrazole keratin dyeing compound and derivatives thereof. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  含有适合染色的介质和至少一种3-取代吡唑角蛋白染料化合物及其衍生物的角蛋白氧化染色组合物。一种角蛋白氧化染色的方法，包括在氧化剂存在下应用这种组合物，以便在足够的时间内发展所需的着色。
• Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof
  申请人：Glenn Wayne Robert

  公开号：US20080098535A1

  公开（公告）日：2008-05-01

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and one or more tricyclic fused 6-5-6 heteroaromatic keratin dyeing compounds having one heteroatom. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  含氧化染料的角蛋白纤维氧化染色组合物，包括适于染色的介质和一个或多个三环融合6-5-6杂环角蛋白染料化合物，其中含有一个杂原子。一种氧化染色角蛋白纤维的方法，包括在氧化剂存在下应用这种组合物，以达到所需的着色时间。
• COMPOUNDS FOR THE TREATMENT OF CANCERS ASSOCIATED WITH HUMAN PAPILLOMAVIRUS
  申请人：Piramal Swati Ajay

  公开号：US20140142159A1

  公开（公告）日：2014-05-22

  The present invention relates to the pyrrolidine substituted with flavone derivatives, represented by the compounds of Formula (I) or a pharmaceutically acceptable salt, a solvate, a stereoisomer or a diastereoisomer thereof for use in the treatment of cancers associated with human papillomavirus. The present invention also relates to the pharmaceutical compositions containing the compounds of Formula (I) for the treatment of cancers associated with human papillomavirus.

  本发明涉及用于治疗与人类乳头瘤病毒相关的癌症的嘧啶替代黄酮衍生物，其由式（I）的化合物或其药学上可接受的盐、溶剂化物、立体异构体或对映异构体表示。本发明还涉及含有式（I）化合物的药物组合物，用于治疗与人类乳头瘤病毒相关的癌症。