Dimethyl-[3-(octahydro-isoindol-2-yl)-propyl]-amine | 96901-02-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: Dimethyl-[3-(octahydro-isoindol-2-yl)-propyl]-amine
• 英文别名: 3-(1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl)-N,N-dimethylpropan-1-amine
• CAS: 96901-02-9
• 化学式: C₁₃H₂₆N₂
• 分子量: 210.363
• InChiKey: KPIFYCALUBLAEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS
  申请人：Dunn William A.

  公开号：US20120141491A1

  公开（公告）日：2012-06-07

  The subject application provides small compounds that are able to increase/enhance autophagy in various cells. These compounds are useful in augmenting existing treatments of various cancers, microbial/viral infections, and neurodegenerative diseases. Thus, the subject application also provides methods of treating various types of cancers, microbial/viral infections, and neurodegenerative diseases.
• [EN] METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS<br/>[FR] MÉTHODES ET COMPOSITIONS POUVANT ÊTRE UTILISÉES DANS LE CADRE DU TRAITEMENT DES CANCERS ET DES INFECTIONS PATHOGÈNES
  申请人：UNIV FLORIDA

  公开号：WO2011019636A2

  公开（公告）日：2011-02-17

  The subject application provides small compounds that are able to increase/enhance autophagy in various cells. These compounds are useful in augmenting existing treatments of various cancers, microbial/viral infections, and neurodegenerative diseases. Thus, the subject application also provides methods of treating various types of cancers, microbial/viral infections, and neurodegenerative diseases.
• [EN] AUTOPHAGY-INDUCING MOLECULES FOR INCREASING INSULIN RELEASE<br/>[FR] MOLÉCULES INDUISANT UNE AUTOPHAGIE PERMETTANT D'AUGMENTER LA LIBÉRATION D'INSULINE
  申请人：UNIV STRASBOURG

  公开号：WO2016119856A1

  公开（公告）日：2016-08-04

  The present invention relates to the use of autophagy-inducing molecules for increasing release or secretion of insulin by pancreatic β cells. It is useful for treating hyperglycemia, associated or not with diabetes.