2-Methoxyethyl 2-hydroxy-2-phenylacetate | 20309-56-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Methoxyethyl 2-hydroxy-2-phenylacetate
• CAS: 20309-56-2
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: LREWUYBQLXKAOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF<br/>[FR] PROCÉDÉS DE PRÉPARATION D'INHIBITEURS D'ACC ET FORMES SOLIDES CORRESPONDANTES
  申请人：GILEAD SCIENCES INC

  公开号：WO2018161022A1

  公开（公告）日：2018-09-07

  The present disclosure provides solid forms, including a salt or co-crystal, of Compound I which exhibits Acetyl-CoA carboxylase ("ACC") inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

  本公开提供了化合物I的固体形式，包括盐或共晶，该化合物表现出乙酰辅酶A羧化酶（"ACC"）抑制活性，并可能在治疗ACC介导的疾病中有用。本文还提供了用于制备化合物I的过程或步骤，以及对所述过程或步骤有用的中间体。
• PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
  申请人：Gilead Sciences, Inc.

  公开号：US20180298025A1

  公开（公告）日：2018-10-18

  The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.