2-(Benzylcarbamothioylamino)benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(Benzylcarbamothioylamino)benzamide
• 化学式: C₁₅H₁₅N₃OS
• 分子量: 285.4
• InChiKey: ILNGJSDXICCBOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  99.2
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• [EN] PHOSPHOLIPASE C INHIBITORS FOR USE IN TREATING INFLAMMATORY DISORDERS<br/>[FR] INHIBITEURS DE PHOSPHLOLIPASE C DESTINES A ETRE UTILISE DANS LE TRAITEMENT DE TROUBLES INFLAMMATOIRES
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2004087685A2

  公开（公告）日：2004-10-14

  This invention is directed to heterocyclyl-substituted anilino phospholipase C inhibitor compounds and enantiomers, diastereomers and pharmaceutically acceptable salts thereof useful in treating or ameliorating an inflammatory disorders and/or restenosis. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions affected by phospholipase modulation.