S,S-diethyl(o-nitro-α-hydroxybenzyl)dithiophosphonate | 88237-86-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S,S-diethyl(o-nitro-α-hydroxybenzyl)dithiophosphonate
• 英文别名: S,S-diethyl 1-hydroxy-o-nitrobenzyldithiophosphonate；S,S-diethyl [hydroxy(2-nitrophenyl)methyl]phosphonodithioate；bis(ethylsulfanyl)phosphoryl-(2-nitrophenyl)methanol
• CAS: 88237-86-9
• 化学式: C₁₁H₁₆NO₄PS₂
• 分子量: 321.358
• InChiKey: KRUKYAILSKQROU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  134
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  S,S'-diethyl 1-trimethylsilyloxy-o-nitrobenzyldithiophosphonate 在 水 作用下， 以 乙醚 为溶剂， 以58.8%的产率得到S,S-diethyl(o-nitro-α-hydroxybenzyl)dithiophosphonate
  参考文献：
  名称：

  Synthesis and reactions of S,S-dialkyl trimethylsilyl dithiophosphites

  摘要：

  S,S-Dialkyl-O-trimethylsilyl dithiophosphites (III)-(VI) have been obtained by reacting dialkyl dithiochlorophosphites with bis(trimethylsilyl)acetamide. Compounds (III)-(VI) react with aldehydes in the presence of catalytic amounts of tertiary amines to give S,S-dialkyl-1-trimethylsilyloxyalkyl-dithiophosphonates (VII)-(IX) and (XII). Hydrolysis of (III) and (V) affords dialkyl dithiophosphites (XVI) and (XVII), which readily add to azomethines and chloral.

  DOI：

  10.1007/bf00960419

文献信息

• Reaction of alkylthiolchlorophosphonites and dialkylchlorodithiophosphites with carbonyl compounds
  作者：N. A. Kardanov、N. P. Provotorova、P. V. Petrovskii、N. N. Godovilov、M. I. Kabachnik

  DOI：10.1007/bf00954671

  日期：1983.9
• KARDANOV, N. A.;PROVOTOROVA, N. P.;PETROVSKIJ, P. V.;GODOVIKOV, N. N.;KAB+, IZV. AN CCCP. CEP. XIM., 1983, N 9, 2114-2121
  作者：KARDANOV, N. A.、PROVOTOROVA, N. P.、PETROVSKIJ, P. V.、GODOVIKOV, N. N.、KAB+

  DOI：——

  日期：——
• KARDANOV N. A.; PROVOTOROVA N. P.; GODOVIKOV N. N.; KABACHNIK M. I., XIMIYA I PRIMENENIE FOSFORORGAN. SOED. TR. 7 BCEC. KONF. PO XIMII FOSFORO+
  作者：KARDANOV N. A.、 PROVOTOROVA N. P.、 GODOVIKOV N. N.、 KABACHNIK M. I.

  DOI：——

  日期：——
• Synthesis and reactions of S,S-dialkyl trimethylsilyl dithiophosphites
  作者：V. A. Al'fonsov、A. G. Trusenev、�. S. Batyeva、A. N. Pudovik、M. A. Pudovik

  DOI：10.1007/bf00960419

  日期：1991.9

  S,S-Dialkyl-O-trimethylsilyl dithiophosphites (III)-(VI) have been obtained by reacting dialkyl dithiochlorophosphites with bis(trimethylsilyl)acetamide. Compounds (III)-(VI) react with aldehydes in the presence of catalytic amounts of tertiary amines to give S,S-dialkyl-1-trimethylsilyloxyalkyl-dithiophosphonates (VII)-(IX) and (XII). Hydrolysis of (III) and (V) affords dialkyl dithiophosphites (XVI) and (XVII), which readily add to azomethines and chloral.