copper triethanolamine | 21545-60-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: copper triethanolamine
• 英文别名: (HOCH2CH2N(CH2CH2O)2) copper(II)；Cupric triethanolamine；copper;2-[2-hydroxyethyl(2-oxidoethyl)amino]ethanolate
• CAS: 21545-60-8
• 化学式: C₆H₁₃NO₃*Cu
• 分子量: 210.72
• InChiKey: HEUUEWZYZFBDIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.0
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  69.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  苯甲酸 、 copper(ll) sulfate pentahydrate 、 copper triethanolamine 在 Na₂CO₃ 作用下， 以 甲醇 为溶剂， 以78%的产率得到[Cu₂(H₂tea)₂(benzoate)₂]·2H₂O
  参考文献：
  名称：

  新型单核、双核和三核铜 (II) 三乙醇胺-羧酸盐配合物的合成和表征

  摘要：

  已经合成了一系列三乙醇胺铜 (II) 羧酸盐配合物，并在结构和光谱上对其进行了表征。化合物的结构和所得配位配合物的核度受试剂的化学计量以及存在于铜配位球中的阴离子配体的空间和电子影响两者的影响。复合物可以以高产率和高纯度制备为高度结晶的固体。我们报告了 (NaCu (CF3COO) 3 (TEAH3)) (1), (Cu (C6H5COO) (TEAH2)) 2 · 2H2 O (2), (Cu3 (CH3COO) 4 (TEAH2) 2) 的光谱和结构数据) (3), (Cu3 (HCOO) 4 (TEAH2) 2) (4) 和 (Cu3 (CF3OO) 2 (TEAH2) 2- (CH3OH) 2) (CF3CO2) 2 (5) (TEAH3 三乙醇胺 (N (CH2CH2OH) ) 3)；(TEAH2) 单去质子化离子；(TEAH) 2 双去质子化离子)。对这些化合物采用了两种方法：羧酸铜

  DOI：

  10.1002/zaac.200500204
• 作为产物：
  描述：

  copper(II) nitrate trihydrate 、 三乙醇胺 以 水 为溶剂， 生成 copper triethanolamine
  参考文献：
  名称：

  Casassas, Enric; Izquierdo-Ridorsa, Anna; Tauler, Roma, Journal of the Chemical Society, Dalton Transactions

  摘要：

  DOI：

文献信息

• Application of biofilm formation inhibiting compounds enhances control of citrus canker
  申请人：University of Florida Research Foundation, Inc.

  公开号：US10111431B2

  公开（公告）日：2018-10-30

  Citrus canker caused by the bacterium Xanthomonas citri subsp. citri (Xac) is an economically important disease of citrus worldwide. Biofilm formation plays an important role in early infection of Xac on host leaves. In this study, we assessed the hypothesis that small molecules able to inhibit biofilm formation reduce Xac infection and enhance the control of citrus canker disease. D-leucine and 3-indolylacetonitrile (IAN) were found to prevent biofilm formation by Xac on different abiotic surfaces and host leaves at a concentration lower than the minimum inhibitory concentration (MIC). Quantitative realtime reverse transcription polymerase chain reaction (qRT-PCR) analysis indicated that IAN repressed expression of chemotaxis/motility-related genes in Xac. In laboratory experiments, planktonic and biofilm cells of Xac treated with D-leucine and IAN, either alone or in combination, were more susceptible to copper (CuSO4) than those untreated. In greenhouse assays, D-leucine and IAN applied alone, or combined with copper reduced both the number of canker lesions and bacterial populations of Xac on citrus host leaves. This study provides the basis for the use of foliar-applied biofilm inhibitors for the control of citrus canker alone or combined with copper-based bactericides.

  柑橘黄单胞菌（Xanthomonas citri subsp. citri，Xac）引起的柑橘腐烂病是全球柑橘的一种重要经济病害。生物膜的形成在 Xac 早期感染寄主叶片时发挥了重要作用。在这项研究中，我们评估了一种假设，即能够抑制生物膜形成的小分子能减少 Xac 感染并增强对柑橘腐烂病的控制。研究发现，D-亮氨酸和 3-吲哚乙腈（IAN）能阻止 Xac 在不同的非生物表面和寄主叶片上形成生物膜，其浓度低于最低抑菌浓度（MIC）。定量实时反转录聚合酶链反应（qRT-PCR）分析表明，IAN 抑制了 Xac 的趋化/运动相关基因的表达。在实验室实验中，单独或联合使用 D-leucine 和 IAN 处理的 Xac 浮游和生物膜细胞比未经处理的细胞更易受铜（CuSO4）的影响。在温室试验中，D-亮氨酸和 IAN 单独使用或与铜结合使用都能减少柑橘寄主叶片上 Xac 腐烂病变的数量和细菌数量。这项研究为使用叶面生物膜抑制剂单独或与铜基杀菌剂联合防治柑橘腐烂病提供了依据。
• Casassas, Enric; Izquierdo-Ridorsa, Anna; Tauler, Roma, Journal of the Chemical Society, Dalton Transactions
  作者：Casassas, Enric、Izquierdo-Ridorsa, Anna、Tauler, Roma

  DOI：——

  日期：——
• PHOTODYNAMIC METHOD OF INHIBITING GROWTH OF A MICROBIAL PLANT PATHOGEN
  申请人：TDA Research, Inc.

  公开号：EP4009789A1

  公开（公告）日：2022-06-15
• Methods and compositions for increasing the efficacy of biologically-active ingredients
  申请人：Windsor Brian J.

  公开号：US20060276339A1

  公开（公告）日：2006-12-07

  The invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, compositions are provided comprising combinations of ectophosphatase inhibitors and active agents. Active agents include antibiotics, fungicides, herbicides, insecticides, chemotherapeutic agents, and plant growth regulators. By increasing the efficacy of active agents, the invention allows use of compositions with lowered concentrations of active ingredients.
• APPLICATION OF BIOFILM FORMATION INHIBITING COMPOUNDS ENHANCES CONTROL OF CITRUS CANKER
  申请人：UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

  公开号：US20160021882A1

  公开（公告）日：2016-01-28

  Citrus canker caused by the bacterium Xanthomonas citri subsp. citri (Xac) is an economically important disease of citrus worldwide. Biofilm formation plays an important role in early infection of Xac on host leaves. In this study, we assessed the hypothesis that small molecules able to inhibit biofilm formation reduce Xac infection and enhance the control of citrus canker disease. D-leucine and 3-indolylacetonitrile (IAN) were found to prevent biofilm formation by Xac on different abiotic surfaces and host leaves at a concentration lower than the minimum inhibitory concentration (MIC). Quantitative real time reverse transcription polymerase chain reaction (qRT-PCR) analysis indicated that IAN repressed expression of chemotaxis/motility-related genes in Xac. In laboratory experiments, planktonic and biofilm cells of Xac treated with D-leucine and IAN, either alone or in combination, were more susceptible to copper (CuSO4) than those untreated. In greenhouse assays, D-leucine and IAN applied alone, or combined with copper reduced both the number of canker lesions and bacterial populations of Xac on citrus host leaves. This study provides the basis for the use of foliar-applied biofilm inhibitors for the control of citrus canker alone or combined with copper-based bactericides.