3,5-dinitro-N-(2-piperazin-1-ylethyl)benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,5-dinitro-N-(2-piperazin-1-ylethyl)benzamide
• 化学式: C13H17N5O5
• 分子量: 323.3
• InChiKey: GXGGTHCFNDPVSF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  136
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• FORMULATIONS FOR INFUSION OF TYPE B LANTIBIOTICS
  申请人：Appleyard Antony Nicholas

  公开号：US20130137630A1

  公开（公告）日：2013-05-30

  Described is a A liquid colloidal pharmaceutical formulation of a type B lantibiotic for infusion or direct injection comprising a type B lantibiotic or a salt thereof, an isotonic aqueous solution comprising a sugar alcohol such as glycerol and/or a saccharide and optionally a buffer, wherein said final formulation for infusion or direct injection is clear of visual particulates.

  描述了一种用于输液或直接注射的B型兰替生物抗生素液体胶体制剂，包括B型兰替生物抗生素或其盐，含有糖醇（如甘油）和/或糖类的等渗水溶液，以及可选的缓冲剂，其中用于输液或直接注射的最终制剂不含有可见颗粒。
• Compounds
  申请人：Wadman Sjoerd Nicolaas

  公开号：US20110294723A1

  公开（公告）日：2011-12-01

  The present disclosure relates to compounds of formula (II): pharmaceutical compositions comprising same and use of the compounds and compositions for the treatment of microbial infection, particularly Methicillin-resistant Staphylococcus aureus (MRSA) infection.

  本公开涉及化合物的公式（II）：包括相同的药物组合物以及用于治疗微生物感染，特别是耐甲氧西林金黄色葡萄球菌（MRSA）感染的化合物和组合物的用途。
• ACTAGARDINE DERIVATIVES
  申请人：Novacta Biosystems Limited

  公开号：EP2393829A1

  公开（公告）日：2011-12-14
• Actagardine Derivatives, and Pharmaceutical Use Thereof
  申请人：Dawson Michael John

  公开号：US20120302728A1

  公开（公告）日：2012-11-29

  Described are lantibiotic-based compounds, pharmaceutical compositions comprising the same and use of the compounds and said compositions, for the treatment of microbial infection, for example Clostridium difficile or Micrococcus luteus infection. The lantibiotic-based compounds have antimicrobial activity and in comparison to one or more of actagardine, actagardine B, deoxyactagardine B and deoxyactagardine have retained activity or improved activity.
• US8729031B2
  申请人：——

  公开号：US8729031B2

  公开（公告）日：2014-05-20