2-[(4-Methylphenyl)methylsulfanyl]propanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[(4-Methylphenyl)methylsulfanyl]propanoic acid
• 化学式: C₁₁H₁₄O₂S
• mdl: MFCD04067635
• 分子量: 210.29
• InChiKey: HGAGZOQIDUIMPU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL AZOLE COMPOUND
  申请人：YAMAMOTO Takashi

  公开号：US20130041000A1

  公开（公告）日：2013-02-14

  Azole compounds represented by formula I: wherein ring A is isoxazole and the like, R1 is a substituted or unsubstituted aryl group and the like, R2 is a hydrogen atom and the like, and R3 is a substituted or unsubstituted alkyl group and the like, and pharmaceutically acceptable salts thereof inhibit the physiological activity of lysophosphatidic acid (LPA), and are useful as for the prophylaxis or treatment of diseases in which inhibition of the physiological activity of LPA is useful for the prophylaxis or treatment thereof, such as diseases involving the LPA receptor.

  公式I所代表的氮唑化合物，其中环A是异噁唑等，R1是取代或未取代的芳基基团等，R2是氢原子等，R3是取代或未取代的烷基基团等，以及其药学上可接受的盐，能够抑制溶血磷脂酸（LPA）的生理活性，可用于预防或治疗需要抑制LPA生理活性的疾病，例如涉及LPA受体的疾病。
• MATRICES OF PROBES AND THEIR PREPARATION
  申请人：BEN-GURION UNIVERSITY OF THE NEGEV

  公开号：EP1218098A1

  公开（公告）日：2002-07-03
• US7517996B2
  申请人：——

  公开号：US7517996B2

  公开（公告）日：2009-04-14
• [EN] MATRICES OF PROBES AND THEIR PREPARATION<br/>[FR] MATRICES DE SONDES ET PREPARATION DE CELLES-CI
  申请人：UNIV BEN GURION

  公开号：WO2001017670A1

  公开（公告）日：2001-03-15

  A matrix for a plurality of probe species, each of which is a first member of a pair-forming group, for binding of a target which is the second member of the pair-forming group, wherein each probe species is confined to a separate and predetermined location in the matrix. The matrix comprises a conductive solid support, on which there is immobilized a conductive film, comprising a polymer or co-polymer composed of electropolymerizable monomers. The conductive film has an inner layer (7), which is in direct contact with the solid support, and comprises probe-free monomers, and an outer layer extending (8) therefrom, which comprises probe-linked monomers.