N,N,N-三甲基-4-(6-苯基-1,3,5-己三烯-1-基)苯基铵对甲苯磺酸盐 | 115534-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N,N,N-三甲基-4-(6-苯基-1,3,5-己三烯-1-基)苯基铵对甲苯磺酸盐
• 英文名称: Tma-dph
• 英文别名: 4-methylbenzenesulfonate;trimethyl-[4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]phenyl]azanium
• CAS: 115534-33-3
• 化学式: C28H31NO3S
• 分子量: 461.6
• InChiKey: ZKARERKEBVSZCX-VMDDUYISSA-M

物化性质

• 熔点：
  237 °C (dec.)(lit.)
• 溶解度：
  在DMF中可溶

计算性质

• 辛醇/水分配系数(LogP)：
  6.07
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险品标志：
  T
• 危险类别码：
  R61
• WGK Germany：
  3

制备方法与用途

生物活性

TMA-DPH 是一种疏水性荧光膜探针 (激发光：355 nm；发射光：430 nm)。

体外研究

接触细胞时，TMA-DPH 立即被整合到质膜中。在细胞内，TMA-DPH 主要集中在溶酶体和高度酸性的晚期内体中。其荧光寿命保持恒定，在同一临界浓度（2 μM）以下为 6.2±0.2 ns，但在更高浓度时显著下降。然而，在超过 5 μM 的浓度下，这种下降速度会变慢。

TMA-DPH 的荧光各向异性与其荧光寿命表现出相似的变化模式。在低至 2 μM 浓度时保持不变（0.283±0.003），但在达到 5 μM 时迅速降至 0.270±0.003，尽管在更高浓度下进一步下降的速度较慢。

文献信息

• A COMPOSITION, SYSTEM AND METHOD FOR REMOVAL OF DETERGENTS FROM AQUEOUS SOLUTIONS
  申请人：DNA GENOTEK INC.

  公开号：US20200316493A1

  公开（公告）日：2020-10-08

  A system, composition, method and kit for removing a detergent, such as an anionic detergent, from an aqueous solution, comprising a salt, a water immiscible alcohol of Formula I: R 1 —OH  (Formula I) where R1 is an optionally substituted, linear, branched or cyclic C4-C12 alkyl; and a water immiscible halocarbon, wherein said halocarbon is miscible with said alcohol of Formula I. The system can be used on aqueous solutions that contain detergents (such as Sodium Dodecyl Sulphate (SDS), for example), and any detergent-associated or detergent-bound molecules that may be present in the aqueous solution, to form an aqueous phase and a non-aqueous phase, for effectively removing the detergent and any detergent-associated or detergent-bound molecules, and sequestering them into the non-aqueous phase.
• [EN] SILICA CORE-SHELL MICROPARTICLES<br/>[FR] MICROPARTICULES NOYAU-ENVELOPPE DE SILICE
  申请人：GLANTREO LTD

  公开号：WO2012110995A1

  公开（公告）日：2012-08-23

  Hybrid silica core - shell microparticles are prepared by growing a porous hybrid silica shell from a mixed silica precursor comprising an alkoxy silica precursor and an organic alkoxy silane precursor onto the surface of non- porous silica particles dispersed in a stabilizing mixed surfactant solution under basic pH conditions, the growth step is repeated a plurality of times. The microparticles are hydrothermally treated in an oil-in-water emulsion system and residual surfactant is removed by calcination or extraction. The final pore diameter of the microparticles is increased by controlled dissolution in an acidic or basic solution.