N-cycloheptyl-2-mercaptonicotinamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-cycloheptyl-2-mercaptonicotinamide
• 英文别名: N-cycloheptyl-2-sulfanylidene-1H-pyridine-3-carboxamide
• 化学式: C₁₃H₁₈N₂OS
• 分子量: 250.36
• InChiKey: HNVKPSDKBQBNDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  73.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Process for depigmenting keratin materials using thiopyridinone compounds
  申请人：L'OREAL

  公开号：US11052028B2

  公开（公告）日：2021-07-06

  The invention relates to cosmetic processes and compositions for depigmenting, lightening and/or whitening keratin materials, in particular the skin, which comprises the application of a cosmetic composition comprising thiopyridinone compounds to keratin materials.

  本发明涉及用于脱色、淡化和/或美白角质材料（尤其是皮肤）的化妆品工艺和组合物，其中包括将包含噻啶酮化合物的化妆品组合物用于角质材料。
• PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS
  申请人：L'Oréal

  公开号：EP2651897A1

  公开（公告）日：2013-10-23
• US9138392B2
  申请人：——

  公开号：US9138392B2

  公开（公告）日：2015-09-22
• [EN] PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS<br/>[FR] PROCÉDÉ DE DÉPIGMENTATION DE MATIÈRES KÉRATINIQUES AU MOYEN DE COMPOSÉS DE THIOPYRIDINONE
  申请人：OREAL

  公开号：WO2012080075A1

  公开（公告）日：2012-06-21

  The invention relates to a cosmetic process for depigmenting, lightening and/or whitening keratin materials, in particular the skin, which comprises the application of a cosmetic composition comprising a compound of formula (I): or its tautomer form of formula (I) in which: R1 and R2, which may be identical or different, denote a radical chosen from: a) a hydrogen atom; b) a C1-C20 alkyl group optionally interrupted with N, S or O, optionally substituted with one or more group(s) chosen from -OR3, -SR3, -NR3R4, -CONHR3; -COOR3; and an aryl group optionally substituted with one or more hydroxyls and/or with one or more C1-C8 alkoxy radicals;c) a C1-C8 alkyl group substituted with a C5-C12 aryl radical optionally substituted with one or more hydroxyls and/or with one or more C1-C8 alkoxy radicals; d) a phenyl group optionally substituted with one or more hydroxyls and/or with one or more C1-C8 alkoxy radicals; R3 denoting H or a C1-C5 alkyl group, R4 denoting H, a C1-C5 hydrocarbon-based group or an acetyl group; it being possible for R1 and R2 to form, with the nitrogen atom which bears them, a ring chosen from pyrrolidine, pyrroline, piperidine, piperazine, morpholine, thiomorpholine and azepine. The invention also relates to the cosmetic use of a compound (I) or (I) as a whitening, lightening and/or depigmenting agent for keratin materials.