(3E)-4-(4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0] hept-1-yl)-3-buten-2-one | 397869-88-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: (3E)-4-(4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0] hept-1-yl)-3-buten-2-one
• 英文别名: 3-Buten-2-one, 4-(4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-；(E)-4-(4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)but-3-en-2-one
• CAS: 397869-88-4
• 化学式: C₁₃H₂₀O₃
• 分子量: 224.3
• InChiKey: VYKLRWGPNUVKNC-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  紫黄素 在 双氧水 、 sodium acetate 作用下， 以 水 为溶剂， 反应 1.0h， 生成 (3E)-4-(4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0] hept-1-yl)-3-buten-2-one
  参考文献：
  名称：

  Generation of Norisoprenoid Flavors from Carotenoids by Fungal Peroxidases

  摘要：

  To biotechnologically produce norisoprenoid flavor compounds, two extracellular peroxidases (MsP1 and MsP2) capable of degrading carotenoids were isolated from the culture supernatants of the basidiomycete Marasmius scorodonius (garlic mushroom). The encoding genes were cloned from genomic DNA and cDNA libraries, and databank homology searches identified MsP1 and MsP2 as members of the so-called "DyP-type" peroxidase family. Wild type enzymes and recombinant peroxidases expressed in Escherichia coli were employed for the release of norisoprenoids; from various terpenoid precursor molecules. Carotenes, xanthophylls, and apocarotenals were subjected to the enzymatic degradation. Released volatile products were characterized by GC-FID and GC-MS, whereas nonvolatile breakdown products were analyzed by means of HPLC-DAD and HPLC-MS. C13 norisoprenoids together with C10 products proved to be the main volatile degradation products in each case.

  DOI：

  10.1021/jf901438m

文献信息

• Polynucleotides encoding carotenoid and apocartenoid biosynthetic pathway enzymes in coffee
  申请人：Tanksley Steven D.

  公开号：US20090178156A1

  公开（公告）日：2009-07-09

  Polynucleotides encoding polypeptides that comprise the biosynthetic pathway for carotenoids and apocarotenoids in the coffee plant are disclosed. Also disclosed are a promoter sequence from a coffee carotenoid gene, and methods for using these polynucleotides, polypeptides, and promoter sequences for gene regulation and the manipulation of flavor, aroma, and other features of coffee beans, as well as the manipulation of photosynthesis in the coffee plant.
• Generation of Norisoprenoid Flavors from Carotenoids by Fungal Peroxidases
  作者：Kateryna Zelena、Björn Hardebusch、Bärbel Hülsdau、Ralf G. Berger、Holger Zorn

  DOI：10.1021/jf901438m

  日期：2009.11.11

  To biotechnologically produce norisoprenoid flavor compounds, two extracellular peroxidases (MsP1 and MsP2) capable of degrading carotenoids were isolated from the culture supernatants of the basidiomycete Marasmius scorodonius (garlic mushroom). The encoding genes were cloned from genomic DNA and cDNA libraries, and databank homology searches identified MsP1 and MsP2 as members of the so-called "DyP-type" peroxidase family. Wild type enzymes and recombinant peroxidases expressed in Escherichia coli were employed for the release of norisoprenoids; from various terpenoid precursor molecules. Carotenes, xanthophylls, and apocarotenals were subjected to the enzymatic degradation. Released volatile products were characterized by GC-FID and GC-MS, whereas nonvolatile breakdown products were analyzed by means of HPLC-DAD and HPLC-MS. C13 norisoprenoids together with C10 products proved to be the main volatile degradation products in each case.

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