4-methyl-N-morpholin-4-ylbenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-N-morpholin-4-ylbenzamide
• 化学式: C₁₂H₁₆N₂O₂
• 分子量: 220.27
• InChiKey: UTKMRLNOXXAVMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Organic reactions with CO generating materials
  申请人：——

  公开号：US20020161266A1

  公开（公告）日：2002-10-31

  The present invention is drawn to a method of performing a one-pot organic reactions including carbon monoxide as reactant, without the use of an external CO gas source, wherein a reaction mixture containing a solid or liquid CO releasing compound, a non-metal substrate and a metal catalyst is exposed to an energy source to release carbon monoxide from the CO releasing compound and wherein carbon atoms of the released carbon monoxide form a bond with the non-metal substrate compound. The present invention is further drawn to a method of preparing chemical libraries and a kit for organic reactions.

  本发明涉及一种在无需使用外部CO气体源的情况下，利用一种含有固体或液体CO释放化合物、非金属基质和金属催化剂的反应混合物，通过暴露于能量源来释放CO释放化合物中的一氧化碳，并且释放的一氧化碳的碳原子与非金属基质化合物形成键的单锅有机反应的方法。本发明还涉及一种制备化学文库和有机反应试剂盒的方法。
• US6958243B2
  申请人：——

  公开号：US6958243B2

  公开（公告）日：2005-10-25
• [EN] SULFONAMIDE DERIVATIVES<br/>[FR] DERIVES SULFONAMIDE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2006005486A1

  公开（公告）日：2006-01-19

  The invention relates to compounds of the general formula (I), wherein R1-R5 and R2’-R4’ are as described in the claims and to pharmaceutically suitable acid additon salts, optical pure enantiomers, racemates or diastereomeric mixtures thereof for the treatment of Alzheimer’s disease or common cancers.