2-[2-[[3-[[2-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethylamino]methyl]phenyl]methylamino]ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one | 1275597-52-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-[2-[[3-[[2-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethylamino]methyl]phenyl]methylamino]ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
• CAS: 1275597-52-8
• 化学式: C₆₈H₇₈N₈O₄
• 分子量: 1071.42
• InChiKey: UEWBPOIBHZFKSX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  80
• 可旋转键数：
  22
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  96.1
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  罗丹明B 以 乙醇 为溶剂， 反应 26.0h， 生成 2-[2-[[3-[[2-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethylamino]methyl]phenyl]methylamino]ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
  参考文献：
  名称：

  Water induced chromogenic and fluorogenic signal modulation in a bi-fluorophore appended acyclic amino-receptor system

  摘要：

  基于无环氨基酸受体的双荧光信号系统3展示了一种水诱导的同时双通道显色和荧光信号调制。其在各种有机溶剂中的微摩尔溶液在微量水存在下，通过水诱导的罗丹明染料去内酯化作用增强了吸收，从而呈现为颜色变化的可视感知。水分子的存在还有助于从激发态的硝基苯并噁二唑荧光团到3中的罗丹明染料的荧光共振能量转移（FRET），并导致发射强度增强到二级数量级。参考化合物2和4在类似条件下无响应，揭示了受体结构变化在光物理过程扰动中的作用。

  DOI：

  10.1039/c0ob00238k

文献信息

• Hg(II) ion specific dual mode signalling in a thiophene derivatized rhodamine based probe and their complexation cooperativity
  作者：Ajoy Pal、Bamaprasad Bag

  DOI：10.1016/j.jphotochem.2012.05.010

  日期：2012.7

  The rhodamine based chemosensor 1 exhibited highly selective and sensitive detection of Hg(II) ion in MeCN-H2O mixture observable through amplified absorption and emission signals with a colour change from colourless to pink. Its thiophenyl subunit plays a predominant role in observed allosteric cooperativity in binding of both the Hg(II) ions of its 1:2 (L:M) complex stoichiometry. The anion induced 'turn-off' signalling responses of the Hg(II)-complex of 1 and subsequent 'turn-on' responses with further addition of Hg(II) here demonstrated its repetitive usability as a probe for Hg(II) ion detection. (C) 2012 Elsevier B.V. All rights reserved.