2-(4-chlorophenyl)sulfanyl-N-(4-fluorophenyl)-2-phenylacetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(4-chlorophenyl)sulfanyl-N-(4-fluorophenyl)-2-phenylacetamide
• 化学式: C₂₀H₁₅ClFNOS
• 分子量: 371.9
• InChiKey: FTSCUVSWGHFKKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES
  申请人：Sun Xiujun

  公开号：US20110251182A1

  公开（公告）日：2011-10-13

  This invention relates to methods of screening for modulators of mammalian cell injury cause by TRPM7 gene and protein activity, compounds that modulate TRPM7 gene and protein activity and methods of treatment of mammalian cell injury using modulators of TRPM7 gene and protein activity.
• US8680137B2
  申请人：——

  公开号：US8680137B2

  公开（公告）日：2014-03-25
• US9566284B2
  申请人：——

  公开号：US9566284B2

  公开（公告）日：2017-02-14
• [EN] AGENTS AND METHODS FOR TREATING ISCHEMIC AND OTHER DISEASES<br/>[FR] AGENTS ET MÉTHODES DE TRAITEMENT DE MALADIES ISCHÉMIQUES ET D'AUTRES MALADIES
  申请人：NONO INC

  公开号：WO2011072275A2

  公开（公告）日：2011-06-16

  This invention relates to methods of screening for modulators of mammalian cell injury cause by TRPM7 gene and protein activity, compounds that modulate TRPM7 gene and protein activity and methods of treatment of mammalian cell injury using modulators of murine TRPM7 gene and protein activity.