Isopropyl N-(2-methoxy-5-methylphenyl)carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Isopropyl N-(2-methoxy-5-methylphenyl)carbamate
• 英文别名: propan-2-yl N-(2-methoxy-5-methylphenyl)carbamate
• 化学式: C₁₂H₁₇NO₃
• 分子量: 223.27
• InChiKey: VCFHXTHGNMORPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] SIGMA RECEPTOR BINDERS<br/>[FR] LIANTS DE RÉCEPTEUR SIGMA
  申请人：UNIV TEXAS

  公开号：WO2017190107A1

  公开（公告）日：2017-11-02

  Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, traumatic brain injury, and neuropathic pain.

  本文提供了治疗疾病的化合物和方法，包括癌症、神经系统疾病、酒精戒断、抑郁和焦虑、创伤性脑损伤以及神经病痛。
• Sigma receptor binders
  申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

  公开号：US10954217B2

  公开（公告）日：2021-03-23

  Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.

  本文特别提供了用于治疗癌症、神经系统疾病、戒酒、抑郁和焦虑以及神经性疼痛等疾病的化合物和方法。
• COMPOUNDS AND METHODS FOR TREATING CANCER, NEUROLOGICAL DISORDERS, ETHANOL WITHDRAWAL, ANXIETY, DEPRESSION, AND NEUROPATHIC PAIN
  申请人：Board of Regents, The University of Texas System

  公开号：US20160280657A1

  公开（公告）日：2016-09-29

  Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
• SIGMA RECEPTOR BINDERS
  申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

  公开号：US20190177301A1

  公开（公告）日：2019-06-13

  Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.