N-(3,4-dimethylphenyl)imidodicarbonimidic diamide | 49872-75-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3,4-dimethylphenyl)imidodicarbonimidic diamide
• 英文别名: 1-(diaminomethylidene)-2-(3,4-dimethylphenyl)guanidine
• CAS: 49872-75-5
• 化学式: C₁₀H₁₅N₅
• mdl: MFCD03615405
• 分子量: 205.26
• InChiKey: VFRGNRZIYZQAOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  103
• 氢给体数：
  3
• 氢受体数：
  1

文献信息

• Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0507317A2

  公开（公告）日：1992-10-07

  The invention presents a biguanide derivative or its salt expressed by a formula: (where R1 and R2 are as defined in Specification), or formula: (where A and R3 is as defined in specification). This biguanide derivative or its salt is preferably used as the effective amount of a disinfectant for humans, animals, medical appliances, etc.

  本发明提出了一种由式表示的双胍衍生物或其盐： (其中 R1 和 R2 如说明书中所定义），或式 (式中A和R3的定义见说明书）。这种双胍衍生物或其盐最好用作人、动物、医疗器械等有效量的消毒剂。
• N2-(3,4-DIMETHYLPHENYL)-6-((4-(P-TOLYL)PIPERAZIN-1-YL)METHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
  申请人：GLUCOX BIOTECH AB

  公开号：US20180022715A1

  公开（公告）日：2018-01-25

  The compound N 2 -(3,4-dimethylphenyl)-6-((4-(p-tolyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamineor a pharmaceutically acceptable salt of said compound. The compound is useful the treatment of a condition or disorder associated with nicotinamide adenine dinucleotide phosphate oxidaseactivity. A pharmaceutical composition comprising the compound.