N-[(4-ethylphenyl)methyl]hexan-1-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(4-ethylphenyl)methyl]hexan-1-amine
• 化学式: C₁₅H₂₅N
• mdl: MFCD07405261
• 分子量: 219.37
• InChiKey: DROYBYKZSJQQAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Compositions and methods for treating tuberculosis
  申请人：The Broad Institute, Inc.

  公开号：US10745356B2

  公开（公告）日：2020-08-18

  The present invention provides compounds for the treatment of a bacterial infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the treatment of a bacterial infection in a subject.

  本发明提供了用于治疗细菌感染的化合物。此外，本发明还提供了使用这些化合物和组合物治疗受试者细菌感染的组合物和方法。
• COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS
  申请人：The Broad Institute, Inc.

  公开号：US20190284140A1

  公开（公告）日：2019-09-19

  The present invention provides compounds for the treatment of a bacterial infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the treatment of a bacterial infection in a subject.
• TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS
  申请人：KEZAR LIFE SCIENCES

  公开号：US20210078974A1

  公开（公告）日：2021-03-18

  Provided herein are triazacyclododecansulfonamide (“TCD”)-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.