1,2-bis(2'-aminophenoxy)-4-t-butylbenzene | 1073342-13-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-bis(2'-aminophenoxy)-4-t-butylbenzene
• 英文别名: 1,2-bis(2'-aminophenoxy)-4-tert-butylbenzene；2-[2-(2-Aminophenoxy)-4-tert-butylphenoxy]aniline；2-[2-(2-aminophenoxy)-4-tert-butylphenoxy]aniline
• CAS: 1073342-13-8
• 化学式: C₂₂H₂₄N₂O₂
• 分子量: 348.445
• InChiKey: ZZZISWOOBLBIEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  70.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,6-Bis(2-formylphenoxymethyl)pyridine 、 1,2-bis(2'-aminophenoxy)-4-t-butylbenzene 以 乙醇 为溶剂， 反应 24.0h， 以38%的产率得到21-Tert-butyl-3,18,25,40-tetraoxa-11,32,46-triazaheptacyclo[40.3.1.04,9.012,17.019,24.026,31.034,39]hexatetraconta-1(45),4,6,8,10,12,14,16,19(24),20,22,26,28,30,32,34,36,38,42(46),43-icosaene
  参考文献：
  名称：

  Nontemplate Synthesis of Two Novel 23-Membered N₃O₄-Donor Macrocycles

  摘要：

  [image omitted] A novel 23-membered heptadentate N3O4 Schiff base ligand has been prepared by [1+1] cyclocondensation of 1,2-bis(2'-aminophenoxy)-4-t-butylbenzene with 2,6-bis(2-formylphenoxymethyl)pyridine by a nontemplate procedure. Treatment of L1 with NaBH4 in EtOH/CHCl3 gave the di-amine macrocycle L2.

  DOI：

  10.1080/00397911003611794
• 作为产物：
  描述：

  1,2-bis(2'-nitrophenoxy)-4-tert-butylbenzene 在 水 、 氯化铵 、 锌 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以77%的产率得到1,2-bis(2'-aminophenoxy)-4-t-butylbenzene
  参考文献：
  名称：

  具有两个新的潜在六齿席夫碱配体的铜（II）和钴（II）配合物的合成和表征。一种铜（II）配合物的X射线晶体结构测定

  摘要：

  两个新的潜在的六齿N 2 O 4 Schiff碱配体2-（（z）-（2-（2-（2-（2-（（z）-3,5-二叔丁基-2-羟基苄亚氨基）苯氧基）苯氧基）苯氧基）苯基亚氨基）甲基）-4,6-二叔丁基苯酚[H 2 L 1 ]和2-（（z）-（2-（2-（2--（（z）-3,5-二叔-由3,5-二叔丁基的反应制得丁基-2-羟基苄叉亚氨基）苯氧基）-5-叔丁基苯氧基）苯基亚氨基）甲基）-4,6-二叔丁基苯酚[H 2 L 2 ]。 -2-羟基苯甲醛分别与1,2-双（2'-氨基苯氧基）苯或1,2-双（2'-氨基苯氧基）-4-叔丁基苯。由配体[H 2 L1和[H 2 L 2 ]与铜（II）和钴（II）盐在甲醇溶液中，在N（Et）3存在下，中性[CuL 1 ]，[CuL 2 ]，[CoL 1 ]和制备[CoL 2 ]复合物。用红外光谱，元素分析，磁化率，质谱，摩尔电导（所有配合物进行了表征Λ米），UV-Vis光谱，并在的情况下[CUL

  DOI：

  10.1016/j.jorganchem.2008.07.012

文献信息

• Characterisation of novel macroacyclic hexadentate (N₄O₂ and N₂O₄) Schiff base ligands and their zinc(II), copper(II) and cobalt(II) complexes, with ligands derived from reduction
  作者：Hassan Keypour、Hadi Amiri Rudbari、Reza Azadbakht、Ebrahim Abouzari Lotf

  DOI：10.3184/030823409x457528

  日期：2009.6

  macrocyclic, hexadentate (N4O2 and N2O4) Schiff base ligands, 1,2-bis(2′-nitrophenoxy)benzene, 1,2-bis (2′-nitrophenoxy)-4-t-butylbenzene), 1,2-bis(2′-aminophenoxy)benzene and 1,2-bis(2′-aminophenoxy)-4-t-butyl-benzene have been synthesised, together with macroacyclic hexadentate ligands formed from their reduction. Zinc(II), copper(II) and cobalt(II) complexes of the Schiff base ligands have also been

  大环六齿（N4O2 和 N2O4）席夫碱配体、1,2-双（2'-硝基苯氧基）苯、1,2-双（2'-硝基苯氧基）-4-叔丁基苯）、1,2-双(2'-氨基苯氧基)苯和1,2-双(2'-氨基苯氧基)-4-叔丁基-苯以及通过它们的还原形成的大无环六齿配体已经合成。席夫碱配体的锌 (II)、铜 (II) 和钴 (II) 配合物也已制备，所有化合物均已通过光谱和元素分析进行​​表征。
• Synthesis and Characterization of Novel 30-Membered Imine and Amine Macrocycles Derived from ortho-Aminophenyl Diamines and 2,6-Diformyl-4-chlorophenol
  作者：Hadi Amiri Rudbari、Ali Moradi

  DOI：10.1055/s-0029-1217087

  日期：2010.1

  Two novel macrocyclic tetraimine-diphenol Schiff bases were synthesized by [2+2] cyclocondensation of ortho-aminophenyl diamines [1,2-bis(2′-aminophenoxy)benzene and 1,2-bis(2′-aminophenoxy)-4-tert-butylbenzene] with 2,6-diformyl-4-chloro­phenol (dcp). Two novel tetraamine-diphenol macrocycles were obtained by reduction of the imine analogues with sodium borohydride in methanol/chloroform. o-aminophenyl

  两个新的大环tetraimine二酚席夫碱被合成[2 + 2]环缩合的邻-氨基苯基二胺[1,2-二（2'-氨基苯氧基）苯和1,2-双（2'-氨基苯氧基）-4-叔丁基苯]与2,6-二甲酰基-4-氯苯酚（dcp）。通过用硼氢化钠在甲醇/氯仿中还原亚胺类似物获得两个新的四胺-二酚大环化合物。 邻氨基苯二胺-2,6-二甲酰基-4-氯苯酚-席夫碱大环-四胺-二苯酚大环
• Four Novel 30-Membered Imine and Amine Macrocycles Derived from<i>Ortho</i>-Aminophenyl Diamines
  作者：Hassan Keypour、Hadi Amiri Rudbari、Reza Azadbakht

  DOI：10.1080/00397910903097328

  日期：2010.4.26

  Two novel macrocyclic tetra-imine-diphenol Schiff base (H2L1 and H2L2) were synthesized by [2+2] cyclocondensation of ortho-aminophenyl diamines [1,2-bis(2'-aminophenoxy)benzene (I) and 1,2-bis(2'-aminophenoxy)-4-t-butylbenzene (II)] with 2,6-diformyl-4-methylphenol. Two novel tetra-amine-diphenol macrocycles (H2L3 and H2L4) have been obtained by reduction of the imine analogs with NaBH4 in MeOH/CHCl3.
• Synthesis, characterization, and electrochemical study of two new macroacyclic Schiff bases and their copper(II) and zinc(II) complexes
  作者：Hassan Keypour、Maryam Shayesteh、Davood Nematollahi、Laura Valencia、Hadi Amiri Rudbari

  DOI：10.1080/00958972.2010.527963

  日期：2010.12.10

  Two new potentially octadentate N2O6 Schiff-base ligands 2-((E)-(2-(2-(2-((E)-2-hydroxy-3-methoxybenzylideneamino)phenoxy)phenoxy)phenylimino)methyl)-6-methoxyphenol H2L1 and 2-((E)-(2-(2-(2-((E)-2-hydroxy-3-methoxybenzylideneamino)phenoxy)-4-tert-butylphenoxy)phenylimino)methyl)-6-methoxyphenol H2L2 were prepared from the reaction of O-Vaniline with 1,2-bis(2'-aminophenoxy)benzene or 1,2-bis(2'-aminophenoxy)-4-t-butylbenzene, respectively. Reactions of H2L1 and H2L2 with copper(II) and zinc(II) salts in methanol in the presence of N(Et)3 gave neutral [CuL1] center dot 0.5CH2Cl2, [CuL2], [ZnL1] center dot 0.5CH2Cl2, and [ZnL2] complexes. The complexes were characterized by IR spectra, elemental analysis, magnetic susceptibility, ESI-MS spectra, molar conductance (m), UV-Vis spectra and, in the case of [ZnL1] center dot 0.5CH2Cl2 and [ZnL2], with 1H- and 13C-NMR. The crystal structure of [ZnL1] center dot 0.5CH2Cl2 has also been determined showing the metal ion in a highly distorted trigonal bipyramidal geometry. The electrochemical behavior of H2L2 and its Cu(II) complex, [CuL2], was studied and the formation constant of [CuL2] was evaluated using cyclic voltammetry. The logarithm value of formation constant of [CuL2] is 21.9.