mono(p-hydroxybenzilidene)-thiocarbohydrazone | 63442-67-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: mono(p-hydroxybenzilidene)-thiocarbohydrazone
• 英文别名: p-hydroxybenzaldehydethiocarbonohydrazone；(4-hydroxy-benzylidene)-thio carbonohydrazide；(4-Hydroxy-benzyliden)-thiocarbonohydrazid；1-amino-3-[(E)-(4-hydroxyphenyl)methylideneamino]thiourea
• CAS: 63442-67-1
• 化学式: C₈H₁₀N₄OS
• 分子量: 210.26
• InChiKey: FCZOVNQNZBTMNJ-BJMVGYQFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  115
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  mono(p-hydroxybenzilidene)-thiocarbohydrazone 在 水 作用下， 生成 1,3-二[(4-氧代-1-环己-2,5-二烯亚基)甲基氨基]硫脲
  参考文献：
  名称：

  Runti, Annali di Chimica, 1956, vol. 46, p. 731,737;

  摘要：

  DOI：
• 作为产物：
  描述：

  硫代卡巴肼 、 对羟基苯甲醛 以 乙醇 、 水 为溶剂， 反应 2.0h， 生成 mono(p-hydroxybenzilidene)-thiocarbohydrazone
  参考文献：
  名称：

  Structural assignment of monothiocarbonohydrazones by1H NMR spectroscopy

  摘要：

  AbstractAnalysis of the 1H NMR spectra of several monothiocarbonohydrazones, some of them synthesized for the first time, shows that they exist as two structural isomers. Whereas, in general, the derivatives of aromatic aldehydes conform to a linear structure, the aliphatic carbonyl derivatives conform to heterocyclic or linear structures, depending on the size of the substituent groups. This dual behaviour is explained in terms of extended conjugation and steric hindrance.

  DOI：

  10.1002/mrc.1270220103

文献信息

• Spectroscopic and analytical evaluation of 1-(di-(2-pyridyl) methylidene-5-(p-hydroxybenzilidene)-thiocarbohydrazone.
  作者：G. Galan、M.T. Morales、M.T. Montaña、J.L. Gomez Ariza

  DOI：10.1016/0022-2860(86)85314-5

  日期：1986.3

  Abstract The synthesis and some of the physico-chemical properties of 1-(di-(2-pyridyl) methylidene)-5-(p-hydroxybenzilidene)-thiocarbohydrazone have been studied. The behaviour against the metallic ions and its possibilities as analytical photometric reagent have been evaluated.

  摘要 研究了 1-(二-(2-吡啶基) 亚甲基)-5-(对羟基苯甲亚甲基)-硫代碳腙的合成和一些理化性质。对金属离子的行为及其作为分析光度试剂的可能性进行了评估。
• ALVAREZ, FERNANDO;DE, PABLOS FERNANDO;GOMEZ, ARIZA JOSE LUIS, TALANTA, 35,(1988) N 6, C. 493-495
  作者：ALVAREZ, FERNANDO、DE, PABLOS FERNANDO、GOMEZ, ARIZA JOSE LUIS

  DOI：——

  日期：——
• Structural assignment of monothiocarbonohydrazones by1H NMR spectroscopy
  作者：G. Rajendran、Sampat R. Jain

  DOI：10.1002/mrc.1270220103

  日期：1984.1

  AbstractAnalysis of the 1H NMR spectra of several monothiocarbonohydrazones, some of them synthesized for the first time, shows that they exist as two structural isomers. Whereas, in general, the derivatives of aromatic aldehydes conform to a linear structure, the aliphatic carbonyl derivatives conform to heterocyclic or linear structures, depending on the size of the substituent groups. This dual behaviour is explained in terms of extended conjugation and steric hindrance.
• Runti, Annali di Chimica, 1956, vol. 46, p. 731,737;
  作者：Runti

  DOI：——

  日期：——