苯甲酸,4-[(2-甲基-1-羰基-2-丙烯基)氨基]- | 15286-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 苯甲酸,4-[(2-甲基-1-羰基-2-丙烯基)氨基]-
• 英文名称: N-p-carboxyphenylmethacrylamide
• 英文别名: p-Carboxyphenylmethacrylamid；4-methacryloylamino-benzoic acid；4-Methacryloylamino-benzoesaeure；N-(meth)acryloyl-p-aminobenzoic acid；N-(4-carboxyphenyl)methacrylamide；4-[(2-Methylacryloyl)amino]benzoic acid；4-(2-methylprop-2-enoylamino)benzoic acid
• CAS: 15286-99-4
• 化学式: C₁₁H₁₁NO₃
• 分子量: 205.213
• InChiKey: KAVKUZZRBQNSGV-UHFFFAOYSA-N

物化性质

• 熔点：
  204-205 °C
• 沸点：
  439.5±37.0 °C(Predicted)
• 密度：
  1.259±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  苯甲酸,4-[(2-甲基-1-羰基-2-丙烯基)氨基]- 、 三丁基氧化锡 在 calcium sulfate 、 水 作用下， 以 甲醇 为溶剂， 以30%的产率得到tributylstannyl 4-(N-(methacryloyl)amino)benzoate * H2O
  参考文献：
  名称：

  双重联络人可能的三烷基甲酸酯的制备和适当的抗剥离电位剂

  摘要：

  已经直接从双（三丁基锡烷基）氧化物或通过酯交换反应制备了具有甲基丙烯酸酯基或马来酸酯衍生物的各种防污三取代有机锡盐。

  DOI：

  10.1016/s0022-328x(00)98613-3
• 作为产物：
  描述：

  4-(β-chloro-isobutyrylamino)-benzoic acid 在 sodium hydroxide 作用下， 生成 苯甲酸,4-[(2-甲基-1-羰基-2-丙烯基)氨基]-
  参考文献：
  名称：

  DE753040

  摘要：

  公开号：

文献信息

• Two-layer imageable element comprising thermally reversible polymers
  申请人：Kodak Polychrome Graphics, L.L.C.

  公开号：US20020160299A1

  公开（公告）日：2002-10-31

  The present invention includes a two-layer imageable element, including: a substrate, a top layer including a first thermally imageable composition including (a) a first thermally sensitive supramolecular polymer or (b) a thermally imageable composition free of the first thermally sensitive supramolecular polymer; and disposed between the substrate and the top layer, a bottom layer including a second thermally imageable composition, which includes a second thermally sensitive supramolecular polymer. The present invention also includes a method of producing the imaged element.

  本发明包括一种双层可成像元件，包括：基板，顶层包括第一热敏感超分子聚合物或不含第一热敏感超分子聚合物的第一热敏感成像组合物；以及位于基板和顶层之间的底层，包括包含第二热敏感超分子聚合物的第二热敏感成像组合物。本发明还包括一种生产成像元件的方法。
• Two paste-type glass ionomer cement
  申请人：Takano Satosi

  公开号：US20060247330A1

  公开（公告）日：2006-11-02

  An object of the present invention is to provide a paste-type cement composition which while retaining adhesion to tooth substance, biocompatibility, surface curability and fluorine sustained-releasability which are the characteristics derived from the conventional glass ionomer cement, reduces water sensitivity which is shortcoming of the conventional glass ionomer cement, enables simple mixing operation, does not adversely affect on the various properties of a cured cement depending on a difference in operators or a skill degree, and can afford various stable properties. There is provided a two paste-type glass ionomer cement comprising a resin-based paste containing a hydrophobic polymerizable monomer and a polymer of acidic group-containing polymerizable monomers which are insoluble to each other, and a water-based paste containing a hydrophilic polymerizable monomer and water which are soluble to each other, in which an acid reactive filler is contained in at least one of pastes.

  本发明的一个目的是提供一种浆糊型水泥组合物，该组合物在保持对牙齿物质的粘附性、生物相容性、表面可固化性和氟释放性这些传统玻璃离子水泥的特性的同时，减少了传统玻璃离子水泥的水敏感性这一缺点，实现了简单的混合操作，不会对已固化水泥的各种性质产生不利影响，不会受到操作者差异或技能水平的影响，并且可以提供各种稳定的性质。提供了一种双浆糊型玻璃离子水泥，包括一种含有疏水性可聚合单体和含有酸性基团可聚合单体聚合物的树脂基浆糊，这些单体在彼此之间不溶解，以及一种含有亲水性可聚合单体和水的水基浆糊，这些单体在彼此之间可溶解，其中至少有一个浆糊中含有酸反应填料。
• Pharmaceutical compositions of beta-lapachone and beta-lapachone analogs with improved tumor targeting potential
  申请人：Ashwell A. Mark

  公开号：US20060034796A1

  公开（公告）日：2006-02-16

  The present invention relates to polymer-modified quinone-containing and carbonyl-containing therapeutic agents, including polymer-modified β-lapachone compounds, and methods of treating cancer by administering the polymer-modified therapeutic agents to a subject. Polymer-modification of therapeutic agents, such as β-lapachone compounds, provides effective transport of polymer-modified therapeutic agents to tumor cells or tumor tissues by exploiting the EPR effect in tumor tissues.

  本发明涉及聚合物修饰的喹酮含量和羰基含量的治疗剂，包括聚合物修饰的β-拉帕霉素化合物，并通过将聚合物修饰的治疗剂给予受试者治疗癌症的方法。聚合物修饰治疗剂，如β-拉帕霉素化合物，通过利用肿瘤组织中的EPR效应，提供了有效的聚合物修饰治疗剂的运输到肿瘤细胞或肿瘤组织的方法。
• ADHESIVE COMPOSITION FOR DENTAL USE
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20210145701A1

  公开（公告）日：2021-05-20

  The present invention provides a dental adhesive composition that, even after photocuring with a high-output LED irradiator, shows high bond strength not only for dentin untreated by phosphoric acid etching but also for dentin treated by phosphoric acid etching. The present invention relates to a dental adhesive composition comprising a phosphoric acid group-containing polymerizable monomer (A), the phosphoric acid group-containing polymerizable monomer (A) comprising: a dihydrogen phosphate monoester group-containing polymerizable monomer (A-1) represented by general formula (1); a hydrogen phosphate diester group-containing polymerizable monomer (A-2) represented by general formula (2); and a phosphoric acid tetraester group-containing polymerizable monomer (A-3) represented by general formula (3).

  本发明提供了一种牙科粘接剂组合物，即使经过高输出LED辐射器的光固化，也能显示出高的粘接强度，不仅适用于未经过磷酸蚀刻处理的牙本质，还适用于经过磷酸蚀刻处理的牙本质。本发明涉及一种牙科粘接剂组合物，包括含磷酸基可聚合单体（A），其中磷酸基可聚合单体（A）包括：一种由通式（1）表示的二氢磷酸单酯基可聚合单体（A-1）；一种由通式（2）表示的氢磷酸双酯基可聚合单体（A-2）；以及一种由通式（3）表示的磷酸四酯基可聚合单体（A-3）。
• POLY(VINYLPYRROLIDONE)-BOUND DIPHENYLHEME
  作者：Eishun Tsuchida、Hiroyuki Nishide、Hiroyuki Yokoyama、Richard Young、Chi K. Chang

  DOI：10.1246/cl.1984.997

  日期：1984.6.5

  trans-5-(o-Aminophehyl)-15-o-[m-(N-imidazolylmethyl)benzamido]phenyl-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphinato iron(II) (diphenylheme) was covalently combined to poly(1-vinyl-2-pyrrolidone); it formed an oxygen adduct in cooled aqueous media.

  反式-5-(邻氨基苯基)-15-o-[m-(N-咪唑基甲基)苯甲酰胺基]苯基-2,8,12,18-四乙基-3,7,13,17-四甲基卟吩合铁(II)（二苯基血红素）与聚（1-乙烯基-2-吡咯烷酮）共价结合；在冷却的水介质中形成氧加成物。