N-(2-dimethylaminoethyl)allylamine | 98433-06-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(2-dimethylaminoethyl)allylamine
• 英文别名: N,N-Dimethyl-N'-allyl-ethylendiamin；N'-allyl-N,N-dimethyl-ethylenediamine；N'-Allyl-N,N-dimethyl-aethylendiamin；N,N-dimethyl-N'-allylethylenediamine；N',N'-dimethyl-N-prop-2-enylethane-1,2-diamine
• CAS: 98433-06-8
• 化学式: C₇H₁₆N₂
• mdl: MFCD11149769
• 分子量: 128.217
• InChiKey: DFLCHQGCURFZRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.714
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  乙醇 、 N-(2-dimethylaminoethyl)allylamine 、 2-氯-2,2-二苯基乙酰氯 生成 ethoxy-diphenyl-acetic acid-[allyl-(2-dimethylamino-ethyl)-amide]
  参考文献：
  名称：

  止痛药。α-烷氧基二苯甲酸的碱性酰胺。

  摘要：

  DOI：

  10.1021/jm00341a018
• 作为产物：
  描述：

  二甲氨基氯乙烷盐酸 、 丙烯胺 在 potassium carbonate 作用下， 以 异丙醇 为溶剂， 反应 3.0h， 生成 N-(2-dimethylaminoethyl)allylamine
  参考文献：
  名称：

  Sequence-Defined Polymers via Orthogonal Allyl Acrylamide Building Blocks

  摘要：

  Biological systems have long recognized the importance of macromolecular diversity and have evolved efficient processes for the rapid synthesis of sequence-defined biopolymers. However, achieving sequence control via synthetic methods has proven to be a difficult challenge. Herein we describe efforts to circumvent this difficulty via the use of orthogonal allyl acrylamide building blocks and a liquid-phase fluorous support for the de novo design and synthesis of sequence-specific polymers. We demonstrate proof-of-concept via synthesis and characterization of two sequence-isomeric 10-mer polymers. (1)H NMR and LCMS were used to confirm their chemical structure while tandem MS was used to confirm sequence identity. Further validation of this methodology was provided via the successful synthesis of a sequence-specific 16-mer polymer incorporating nine different monomers. This strategy thus shows promise as an efficient approach for the assembly of sequence-specific functional polymers.

  DOI：

  10.1021/ja507262t

文献信息

• [EN] ABSORBENT COMPOSITIONS INCLUDING AMINO-SILOXANES<br/>[FR] COMPOSITIONS D'ABSORBANT COMPRENANT DES AMINOSILOXANES
  申请人：GE OIL & GAS INC

  公开号：WO2018190815A1

  公开（公告）日：2018-10-18

  An absorbent composition including an amino-siloxane is presented. The amino- siloxane includes structure (I): wherein R1 is independently at each occurrence a C1-C6 aliphatic or aromatic radical; R2 is independently at each occurrence a C2-C10 aliphatic or aromatic radical; and R3 is independently at each occurrence a C1-C18 aliphatic or aromatic radical or R4, wherein R4 comprises structure (II): wherein X is independently at each occurrence an electron donating group; and n is at least 1. Methods of reducing an amount of carbon dioxide in a process stream using the absorbent composition are also presented.

  提供了一种包含氨基硅氧烷的吸收剂组合物。氨基硅氧烷包括结构（I）：其中R1在每次出现时独立地为C1-C6脂肪或芳香基团；R2在每次出现时独立地为C2-C10脂肪或芳香基团；R3在每次出现时独立地为C1-C18脂肪或芳香基团或R4，其中R4包括结构（II）：其中X在每次出现时独立地为电子给体基团；n至少为1。还提供了使用该吸收剂组合物减少工艺流中二氧化碳量的方法。
• Dihydrobenzothiophenes
  申请人：Finsinger Dirk

  公开号：US20070219246A1

  公开（公告）日：2007-09-20

  Compounds of the formula (I) in which W, R 1 , R 2 , R 3 , R 4 , and q have the meanings indicated in Claim 1 , can be employed, inter alia, for the treatment of tumours.

  式(I)中W、R1、R2、R3、R4和q的含义如权利要求书1所示的化合物，可以用于治疗肿瘤等疾病。
• Process for preparation of aminopropylalkoxysilane
  申请人：SHOWA DENKO KABUSHIKI KAISHA

  公开号：EP0382258A1

  公开（公告）日：1990-08-16

  A process for the preparation of an aminopropyl­alkoxysilane, which comprises reacting a hydrosilane compound with an allylamine compound in the presence of at least one member selected from the group consisting of phosphorus compounds having a phosphorus-nitrogen bond, which are represented by the following formulae: wherein Z¹, Z², Z³, Z⁴, Z⁵ and Z⁶ independently represent a hydrogen atom, an aliphatic hydrocarbon group having 1 to 8 carbon atoms, an alicyclic hydrocarbon group having 5 to 8 carbon atoms or an aromatic hydrocarbon group, and a rhodium compound. According to this process, the aminopropylalkoxy­ silane can be prepared in a high yield at a low cost and a high efficiency, while controlling the formation of the β-compound to a very low level.

  一种氨基丙基烷氧基硅烷的制备方法，包括在至少一种选自具有磷-氮键的磷化合物的成员存在下，使氢硅烷化合物与烯丙基胺化合物反应，这些磷化合物由下式表示： 其中 Z¹、Z²、Z³、Z⁴、Z⁵ 和 Z⁶ 各自代表氢原子、具有 1 至 8 个碳原子的脂族烃基、具有 5 至 8 个碳原子的脂环烃基或芳香烃基、 和一种铑化合物。 根据该工艺，可以低成本、高效率、高产率地制备氨基丙基烷氧基硅烷，同时将 β-化合物的形成控制在极低水平。
• Sequence-defined polymers and methods of making same and using same
  申请人：Cornell University

  公开号：US11384205B2

  公开（公告）日：2022-07-12

  Methods of making sequence-defined polymers and sequence-defined polymers. The methods are based on the orthogonal reactivity of monomers having at least two different functional groups. The sequence-defined polymers can be used in various applications. For example, the SDPs (e.g., pH sensitive SDPs) are used in cell lysis methods or as molecular vehicles to transport drug cargo into cells.

  制造序列确定的聚合物和序列确定的聚合物的方法。这些方法基于至少具有两种不同官能团的单体的正交反应性。序列确定的聚合物可用于各种用途。例如，序列定义聚合物（如 pH 敏感序列定义聚合物）可用于细胞裂解方法或作为分子载体将药物运送到细胞中。
• Pharmaceutical compounds
  申请人：OLIN MATHIESON

  公开号：US02862965A1

  公开（公告）日：1958-12-02