1-(3-Pyridyl)-5-mercaptotetrazol | 62770-11-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(3-Pyridyl)-5-mercaptotetrazol
• 英文别名: 1-pyridin-3-yl-1,4-dihydro-tetrazole-5-thione；1-(pyridin-3-yl)-1H-tetrazole-5-thiol；1-pyridin-3-yl-2H-tetrazole-5-thione
• CAS: 62770-11-0
• 化学式: C₆H₅N₅S
• mdl: MFCD01934963
• 分子量: 179.205
• InChiKey: OFGJTUHYIGMNPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  85
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Uracil derivatives and use thereof in photographic products and processes
  申请人：POLAROID CORPORATION

  公开号：EP0071282A2

  公开（公告）日：1983-02-09

  There are described novel compounds which are represented by the formula wherein R is -CH2-A- or -CH2- = A; A is sulfur or selenium; X represents the nonmetallic atoms necessary to form a nucleus which completes a five or six membered heterocyclic moiety; R, is H or lower alkyl; R2 is H or a hydrolyzable group; and R3 is H, alkyl or a hydrolyzable group. The compounds are useful in photographic applications and provide controlled release of a photographically useful material during processing of photographic elements with an aqueous alkaline processing composition.

  所述新型化合物由以下式子表示 其中 R 是-CH2-A-或- - = A；A 是硫或硒；X 代表形成核所需的非金属原子，该核完成一个五或六成员杂环分子；R 是 H 或低级烷基；R2 是 H 或可水解基团；R3 是 H、烷基或可水解基团。这些化合物在摄影应用中非常有用，可在使用水性碱性冲洗组合物冲洗照片元件时，控制释放对摄影有用的材料。
• Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0240015A2

  公开（公告）日：1987-10-07

  Carbostyril derivatives and salts thereof represented by the general formula (1), including some known compounds, possess activities for inhibiting adhesion of thrombocytes. Some carbostyril derivatives having chemical structural formulas similar to those of carbostyril derivatives and salts thereof represented by the general formula (1) have been known in the prior art references, however above-mentioned pharmacological activities have not been known yet up to the date. Processes for preparing carbostyril derivatives offormu- la (1), a pharmaceutical composition containing them, or a salt thereof, as active ingredient, and their use in the preparation of a medicament for inhibiting adhesion of thrombocytes are also disclosed.

  通式(1)代表的羧基吡啶衍生物及其盐类，包括一些已知化合物，具有抑制血小板粘附的活性。 一些羧基吡啶衍生物的化学结构式与通式(1)代表的羧基吡啶衍生物及其盐类相似，在现有技术参考文献中已为人所知，但上述药理活性至今尚未为人所知。 本发明还公开了制备通式(1)代表的羧基吡啶衍生物、含有它们或其盐类作为活性成分的药物组合物的工艺，以及它们在制备抑制血小板粘附的药物中的用途。
• US4350754A
  申请人：——

  公开号：US4350754A

  公开（公告）日：1982-09-21
• US4442290A
  申请人：——

  公开号：US4442290A

  公开（公告）日：1984-04-10
• US5008274A
  申请人：——

  公开号：US5008274A

  公开（公告）日：1991-04-16