tris(6-methyl-3-sulfophenyl)phosphine | 172655-79-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tris(6-methyl-3-sulfophenyl)phosphine
• 英文别名: tris(6-methyl-3-sulphophenyl)phosphine；tris(6-methyl-3-sulfonatophenyl)phosphine；3-Bis(2-methyl-5-sulfophenyl)phosphanyl-4-methylbenzenesulfonic acid
• CAS: 172655-79-7
• 化学式: C₂₁H₂₁O₉PS₃
• 分子量: 544.564
• InChiKey: UPURIRCSBGYKPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  188
• 氢给体数：
  3
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  tris(6-methyl-3-sulfophenyl)phosphine 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 Trinatrium-3,3',3''-phosphantriyltris(4-methylbenzolsulfonat)
  参考文献：
  名称：

  True water soluble palladium-catalyzed Heck reactions in aqueous–organic biphasic media

  摘要：

  A stable water soluble palladium catalyst has been demonstrated for the Heck reaction in a biphasic medium (water-non-polar organic solvent). Biphasic Heck reactions reported till now generally employ a non-polar solvent along with an aqueous polar water miscible organic solvent as the second phase. The efficiency of the Pd complex of TOTPS [Trisodium salt of tri-(ortho-tolyl) phosphine tri sulfonate] for the vinylation of different aryl iodides and olefins is demonstrated. The advantages of a co-solvent for this biphasic system have also been shown. The catalyst has been recycled efficiently retaining the activity with negligible loss of catalyst and without leaching of the Pd. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.067
• 作为产物：
  描述：

  三(邻甲基苯基)磷 在 硫酸 作用下， 反应 72.0h， 生成 tris(6-methyl-3-sulfophenyl)phosphine
  参考文献：
  名称：

  True water soluble palladium-catalyzed Heck reactions in aqueous–organic biphasic media

  摘要：

  A stable water soluble palladium catalyst has been demonstrated for the Heck reaction in a biphasic medium (water-non-polar organic solvent). Biphasic Heck reactions reported till now generally employ a non-polar solvent along with an aqueous polar water miscible organic solvent as the second phase. The efficiency of the Pd complex of TOTPS [Trisodium salt of tri-(ortho-tolyl) phosphine tri sulfonate] for the vinylation of different aryl iodides and olefins is demonstrated. The advantages of a co-solvent for this biphasic system have also been shown. The catalyst has been recycled efficiently retaining the activity with negligible loss of catalyst and without leaching of the Pd. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.067

文献信息

• METHOD FOR PRODUCING 2,7-OCTADIEN-1-OL
  申请人：KURARAY CO., LTD.

  公开号：US20160046549A1

  公开（公告）日：2016-02-18

  Provided is a simple and industrially advantageous method for producing 2,7-octadien-1-ol, in which an expensive palladium catalyst is recovered in high efficiency and the reaction rate per atom of palladium is enhanced. Specifically, provided is a method for producing 2,7-octadien-1-ol by subjecting butadiene and water to a telomerization in the presence of a palladium catalyst containing a water-soluble triarylphosphine having two or more sulfonate groups in the molecule and a palladium compound, a tertiary amine, and carbon dioxide, including a step of mixing the telomerization solution obtained by the telomerization with an organic solvent having a dielectric constant at 25° C. of 2 to 18, followed by carrying out phase separation in the presence of carbon dioxide, thereby obtaining 2,7-octadien-1-ol from an organic phase while recovering an aqueous phase including the palladium catalyst. By this production method, the selectivity for 2,7-octadien-1-ol is enhanced.

  提供了一种简单且在工业上具有优势的生产2,7-辛二烯-1-醇的方法，其中昂贵的钯催化剂以高效率回收，并且增强了每个钯原子的反应速率。具体而言，提供了一种通过在存在包含具有两个或更多磺酸基团的水溶性三芳基膦和钯化合物、三级胺和二氧化碳的钯催化剂的情况下，使丁二烯和水经过缩聚反应来生产2,7-辛二烯-1-醇的方法，包括将通过缩聚反应获得的缩聚溶液与在25°C时具有介电常数为2到18的有机溶剂混合的步骤，然后在二氧化碳的存在下进行相分离，从而从有机相中获得2,7-辛二烯-1-醇，同时回收包括钯催化剂的水相。通过这种生产方法，对2,7-辛二烯-1-醇的选择性得到增强。
• BIS(6-METHYL-3-SULPHOPHENYL)(2-METHYLPHENYL)PHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD.

  公开号：US20160052948A1

  公开（公告）日：2016-02-25

  Provided are a water-soluble triarylphosphine for a palladium catalyst, which has high selectivity in a telomerization reaction and is easily recovered with efficiency, an ammonium salt thereof, and a method for efficiently producing the same. Specifically, provided are bis(6-methyl-3-sulphophenyl)(2-methylphenyl)phosphine; a bis(6-methyl-3-sulphonatophenyl)(2-methylphenyl)phosphine diammonium salt obtained by reacting the phosphine with a tertiary amine having a total of 3 to 27 carbon atoms in groups bonded to one nitrogen atom; and a method for producing the same.

  提供一种水溶性三芳基膦，用于钯催化剂，在缩聚反应中具有高选择性且易于高效回收的铵盐，以及有效生产该铵盐的方法。具体来说，提供了双(6-甲基-3-磺酸苯基)(2-甲基苯基)膦；通过将该膦与具有总共3至27个碳原子的基团与一个氮原子键合的三级胺反应得到的双(6-甲基-3-磺酸苯基)(2-甲基苯基)膦二铵盐；以及生产该铵盐的方法。
• 비스(6-메틸-3-술포페닐)(2-메틸페닐)포스핀 및 그 암모늄염 그리고 그들의 제조방법
  申请人：KURARAY CO., LTD. 주식회사 쿠라레(519980803653)

  公开号：KR20150133731A

  公开（公告）日：2015-11-30

  텔로머화 반응에 있어서 선택성이 높고, 또한 효율적으로 회수하기 쉬운 팔라듐 촉매용의 수용성 트리아릴포스핀 및 그 암모늄염 그리고 그들의 효율적인 제조 방법을 제공한다. 구체적으로는, 비스(6-메틸-3-술포페닐)(2-메틸페닐)포스핀, 그리고, 그 포스핀과, 질소 1 원자에 결합하는 기의 총탄소수가 3 〜 27 인 제 3 급 아민을 반응하여 얻어지는, 비스(6-메틸-3-술포나토페닐)(2-메틸페닐)포스핀2 암모늄염, 그리고 그들의 제조 방법을 제공한다.

  本发明提供了对于端粒酶反应具有高度选择性和易于高效回收的钯催化剂所需的可溶性三芳基膦及其铵盐以及它们的高效制备方法。具体地，本发明提供了通过反应双(6-甲基-3-苯基丙基)(2-甲基苯基)膦和第三级胺，其总碳数为3-27，并结合氮原子的基团得到的双(6-甲基-3-苯基丙基)(2-甲基苯基)膦二铵盐及其制备方法。
• Bis(6-methyl-3-sulphophenyl)(2-methylphenyl)phosphine, ammonium salt thereof, and method for producing same
  申请人：KURARAY CO., LTD.

  公开号：US11021499B2

  公开（公告）日：2021-06-01

  Provided are a water-soluble triarylphosphine for a palladium catalyst, which has high selectivity in a telomerization reaction and is easily recovered with efficiency, an ammonium salt thereof, and a method for efficiently producing the same. Specifically, provided are bis(6-methyl-3-sulphophenyl)(2-methylphenyl)phosphine; a bis(6-methyl-3-sulphonatophenyl)(2-methylphenyl)phosphine diammonium salt obtained by reacting the phosphine with a tertiary amine having a total of 3 to 27 carbon atoms in groups bonded to one nitrogen atom; and a method for producing the same.

  本发明提供了一种在端粒化反应中具有高选择性且易于高效回收的钯催化剂用水溶性三芳基膦、其铵盐以及高效生产该催化剂的方法。具体地说，提供了双(6-甲基-3-磺酸苯基)(2-甲基苯基)膦；一种双(6-甲基-3-磺酸苯基)(2-甲基苯基)膦二铵盐，该二铵盐是通过将该膦与具有与一个氮原子键合的共 3 至 27 个碳原子的基团的叔胺反应而得到的；以及生产该二铵盐的方法。
• US6051738A
  申请人：——

  公开号：US6051738A

  公开（公告）日：2000-04-18