N-(4-环己基苯基)-4,5-二氢-1H-咪唑-2-胺 | 71576-66-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-(4-环己基苯基)-4,5-二氢-1H-咪唑-2-胺
• 中文别名: S(-)-3,3-二甲基噁丙环-2-甲基4-硝基苯酸酯
• 英文名称: 2-(p-Cyclohexylphenylamino)-2-imidazoline
• 英文别名: N-(4-cyclohexylphenyl)-4,5-dihydro-1H-imidazol-2-amine
• CAS: 71576-66-4
• 化学式: C₁₅H₂₁N₃
• 分子量: 243.352
• InChiKey: DNWWODFFEFZASF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  36.4
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-环己苯胺 以 二氯甲烷 、 乙腈 为溶剂， 反应 25.5h， 生成 N-(4-环己基苯基)-4,5-二氢-1H-咪唑-2-胺
  参考文献：
  名称：

  Synthesis and pharmacological investigation of new substituted guanidines and 2-amino-2-imidazolines

  摘要：

  DOI：

  10.1007/bf00763627

文献信息

• 2-Arylamino-hexahydropyrimidines, compositions containing same, and
  申请人：Duphar International B.V.

  公开号：US04396617A1

  公开（公告）日：1983-08-02

  The invention relates to novel 2-aryliminohexahydropyrimidines and imidazolidines, of the formula ##STR1## as well as to salts and complexes thereof, having fungicidal activity. These compounds are particularly active against rust of beans, brown rust of wheat and mildew on cereals. After having been processed into compositions, the compounds of the invention can successfully be used to prevent or control mould infections in agriculture and horticulture in a dosage of 200-1000 g of active substance per hectare. Very active fungicides are, for example, 2-(4-cyclohexyl-phenyl) iminohexahydropyrimidine and 2-(4-n-hexyl-phenyl) iminohexahydropyrimidine, as well as the sulphuric acid salts of these compounds and complexes with zinc salts.

  本发明涉及新型2-芳基亚胺基六氢嘧啶和咪唑啉，其化学式为##STR1##以及其盐和配合物，具有杀真菌活性。这些化合物特别对豆锈病、小麦褐锈病和谷类粉病活性很高。在加工成配方后，本发明的化合物可以成功地用于农业和园艺中预防或控制霉菌感染，每公顷用量为200-1000克活性物质。非常活性的杀菌剂包括2-(4-环己基苯基)亚胺基六氢嘧啶和2-(4-正己基苯基)亚胺基六氢嘧啶，以及这些化合物的硫酸盐和锌盐配合物。
• 2-Arylimino-imidazolidines, compositions containing same, and method of
  申请人：Duphar International Research B.V.

  公开号：US04374143A1

  公开（公告）日：1983-02-15

  The invention relates to novel 2-aryliminohexahydropyrimidines and imidazolidines, of the formula ##STR1## as well as to salts and complexes thereof, having fungicidal activity. These compounds are particularly active against rust of beans, brown rust of wheat and mildew on cereals. After having been processed into compositions, the compounds of the invention can successfully be used to prevent or control mould infections in agriculture and horticulture in a dosage of 200-1000 g of active substance per hectare. Very active fungicides are, for example, 2-(4-cyclohexyl-phenyl) iminohexahydropyrimidine and 2-(4-n-hexyl-phenyl) iminohexahydropyrimidine, as well as the sulphuric acid salts of these compounds and complexes with zinc salts.

  本发明涉及一种新型的2-芳基亚胺基六氢嘧啶和咪唑啉，其化学式为##STR1##以及其盐和配合物，具有杀菌活性。这些化合物特别对豆锈、小麦棕色锈和谷类霉菌活性较高。在制成组合物后，本发明的化合物可成功用于预防或控制农业和园艺中的霉菌感染，每公顷用量为200-1000克活性物质。非常活性的杀菌剂包括2-(4-环己基苯基)亚胺基六氢嘧啶和2-(4-n-己基苯基)亚胺基六氢嘧啶，以及这些化合物的硫酸盐和锌盐配合物。
• Novel 2-arylamino-hexahydropyrimidines and -imidazolidines, salts and complexes thereof, method of preparing the novel compounds and fungicidal compositions which contain the novel compounds
  申请人：DUPHAR INTERNATIONAL RESEARCH B.V

  公开号：EP0001663B1

  公开（公告）日：1982-05-12
• US4374143A
  申请人：——

  公开号：US4374143A

  公开（公告）日：1983-02-15
• US4396617A
  申请人：——

  公开号：US4396617A

  公开（公告）日：1983-08-02