4-isopropoxy-benzoic acid methylamide | 70772-62-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-isopropoxy-benzoic acid methylamide
• 英文别名: 4-Isopropoxy-benzoesaeure-methylamid；4-isopropoxy-N-methylbenzamide；N-methyl-4-propan-2-yloxybenzamide
• CAS: 70772-62-2
• 化学式: C₁₁H₁₅NO₂
• mdl: MFCD07139418
• 分子量: 193.246
• InChiKey: CHOZMKYJQGPDSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PTPN11 INHIBITORS
  申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

  公开号：US20200048249A1

  公开（公告）日：2020-02-13

  The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.

  本发明涉及一种作为PTPN11抑制剂用于治疗或预防癌症和其他PTP介导疾病的化合物。本文披露了基于吡唑吡唑啉的新化合物和化合物，以及它们作为药物治疗疾病的应用。
• HEPATITIS C VIRUS INHIBITORS
  申请人：Or Yat Sun

  公开号：US20100260715A1

  公开（公告）日：2010-10-14

  The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
• US5846990A
  申请人：——

  公开号：US5846990A

  公开（公告）日：1998-12-08