2-chloro-N-(2-{[(4-methylphenyl)methyl]sulfanyl}ethyl)acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloro-N-(2-{[(4-methylphenyl)methyl]sulfanyl}ethyl)acetamide
• 英文别名: 2-chloro-N-[2-[(4-methylphenyl)methylsulfanyl]ethyl]acetamide
• 化学式: C₁₂H₁₆ClNOS
• mdl: MFCD06655673
• 分子量: 257.78
• InChiKey: BJHCFWDTXAWTGA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.416
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR ANALYZING IMAGING AGENT, PRECURSOR OF IMAGING AGENT, OR INTERMEDIATE OF IMAGING AGENT
  申请人：INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C.

  公开号：US20170115259A1

  公开（公告）日：2017-04-27

  A high performance liquid chromatography method of an imaging agent, a precursor of the imaging agent, or an intermediate of the imaging agent is revealed. Instead of using the same eluent, a first eluent with a lower proportion of methanol is used to elute target compounds. Then a second eluent having a higher ratio of methanol ranging from 95-99% is used to elute for at least 15 minutes. Next use the first eluent again to elute for at least 60 minutes. Thus the target compounds are retained stably in the column and retention time of respective reproductive characteristic peak is obtained.