申请人:Kyowa Medex CO., LTD.
公开号:EP2604699A1
公开(公告)日:2013-06-19
It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising: reacting glycated hemoglobin in the hemoglobin-containing sample with a proteolytic enzyme in the presence of at least one salt selected from the group consisting of a pyridinium salt, a phosphonium salt, an imidazolium salt, and an isoquinolinium salt; reacting the obtained reaction product with fructosyl peptide oxidase; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately measuring glycated hemoglobin in a hemoglobin-containing sample.
本发明提供一种测量含血红蛋白样品中糖化血红蛋白的方法,包括:在至少一种选自吡啶鎓盐、鏻盐、咪唑鎓盐和异喹啉鎓盐组成的组中的盐存在下,使含血红蛋白样品中的糖化血红蛋白与蛋白水解酶反应;使得到的反应产物与果糖肽氧化酶反应;测量生成的过氧化氢。本发明提供了一种精确测量含血红蛋白样品中糖化血红蛋白的方法。