4-(3-Hydroxy-2,3-dimethylbutan-2-yl)phenol | 6337-72-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(3-Hydroxy-2,3-dimethylbutan-2-yl)phenol
• CAS: 6337-72-0
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.27
• InChiKey: GOFIPVBGDILKFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Deuterated fingolimod
  申请人：Liu Julie F.

  公开号：US20090176744A1

  公开（公告）日：2009-07-09

  This invention relates to novel compounds that are deuterated derivatives of fingolimod and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a lysophospholipid edg1 (S1P1) receptor agonist, such as fingolimod.
• DEUTERATED FINGOLIMOD
  申请人：Liu Julie F.

  公开号：US20120141513A1

  公开（公告）日：2012-06-07

  This invention relates to novel compounds that are deuterated derivatives of fingolimod and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a lysophospholipid edg1 (S1P1) receptor agonist, such as fingolimod.