[(2,3-Dichlorophenyl)methyl](propyl)amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(2,3-Dichlorophenyl)methyl](propyl)amine
• 英文别名: N-[(2,3-dichlorophenyl)methyl]propan-1-amine
• 化学式: C₁₀H₁₃Cl₂N
• mdl: MFCD07407645
• 分子量: 218.12
• InChiKey: AWBDGXFLNNEVBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• NOVEL DIAZABICYCLONONENE DERIVATIVE
  申请人：Actelion Pharmaceuticals Ltd.

  公开号：EP1824851A2

  公开（公告）日：2007-08-29
• QUINOLINE-8-SULFONAMIDE DERIVATIVES HAVING AN ANTICANCER ACTIVITY
  申请人：Agios Pharmaceuticals, Inc.

  公开号：EP2448582B1

  公开（公告）日：2017-04-19
• [EN] BICYCLONONENE DERIVATIVES<br/>[FR] DERIVES DE BICYCLONONENE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2006021399A2

  公开（公告）日：2006-03-02

  The invention relates to novel bicyclononene derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
• [EN] BICYLONONENE DERIVATIVES<br/>[FR] DERIVES DE BICYCLONONENE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2006021401A2

  公开（公告）日：2006-03-02

  The invention relates to bicyclononene derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
• [EN] BICYCLIC FIVE-MEMBERED HETEROARYL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS<br/>[FR] DERIVES HETEROARYLE BICYCLIQUES A CINQ CHAINONS ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE LA RENINE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2006092268A1

  公开（公告）日：2006-09-08

  [EN] The invention relates to novel five-membered heteroaryl derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions comprising one or more of those compounds and especially their use as inhibitors of renin.
  [FR] La présente invention concerne de nouveaux dérivés hétéroaryle à cinq chaînons et leur utilisation en tant que principes actifs dans la préparation de compositions pharmaceutiques. Cette invention concerne également des aspects connexes, y compris des procédés de préparation des composés, des compositions pharmaceutiques comprenant un ou plusieurs de ces composés et tout particulièrement leur utilisation en tant qu'inhibiteurs de la rénine.