[(E)-4-(tert-butylamino)-4-oxobut-2-en-2-yl] 2-amino-5-chlorobenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(E)-4-(tert-butylamino)-4-oxobut-2-en-2-yl] 2-amino-5-chlorobenzoate
• 化学式: C₁₅H₁₉ClN₂O₃
• 分子量: 310.77
• InChiKey: PCHJWSNHEIWDTG-VQHVLOKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  81.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• NOVEL ANNELATED BENZAMIDES
  申请人：Boehringer Ingelheim International GmbH

  公开号：US20180186774A1

  公开（公告）日：2018-07-05

  The present invention relates to compounds of formula (I) wherein R 1 , R 2 , and Z − have one of the meanings as indicated in the specification or a pharmaceutically acceptable salt thereof, to the use of compounds of formula (I) as a medicament, to pharmaceutical composition comprising at least one compound of formula (I), as well as to medicament combinations containing one or more compounds of formula (I).