[EN] ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE<br/>[FR] RÉACTIFS D'ALKYLATION ÉLECTROPHILES, LEUR PRÉPARATION ET LEUR UTILISATION
申请人:HOVIONE INT LTD
公开号:WO2012131286A1
公开(公告)日:2012-10-04
The present invention provides electrophilic alkylating reagents of formula II, wherein is an aryl group, R2 is an alkyl group, R3 is a substituted phenyl group, wherein the number of substituents (n) is greater than 2 and R4 is an anion, and salts thereof, methods for their preparation and methods for the preparation of alkylated biologically active compounds using such reagents.
本发明提供了公式II的亲电烷基化试剂,其中为芳基,R2为烷基,R3为取代苯基,其中取代基的数量(n)大于2,R4为阴离子,以及它们的盐,其制备方法和使用这种试剂制备烷基化生物活性化合物的方法。