N-CBZ-3-乙胺基哌啶 | 1131594-94-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-CBZ-3-乙胺基哌啶
• 中文别名: 3-乙基氨基哌啶-1-羧酸苄酯；N-CBZ-3-乙氨基哌啶
• 英文名称: benzyl 3-(ethylamino)piperidine-1-carboxylate
• CAS: 1131594-94-9
• 化学式: C₁₅H₂₂N₂O₂
• 分子量: 262.352
• InChiKey: AUHWJUIFKOMNQG-UHFFFAOYSA-N

物化性质

• 沸点：
  388.2±42.0 °C(Predicted)
• 密度：
  1.10±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2933399090

文献信息

• HETEROCYCLIC TYROSINE KINASE INHIBITORS
  申请人：Hopkins Brian T.

  公开号：US20130345192A1

  公开（公告）日：2013-12-26

  The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same.

  本发明提供了作为Tec家族激酶抑制剂的化合物，其组成物以及使用它们的方法。
• US9273028B2
  申请人：——

  公开号：US9273028B2

  公开（公告）日：2016-03-01
• [EN] HETEROCYCLIC TYROSINE KINASE INHIBITORS<br/>[FR] INHIBITEURS DE TYROSINE KINASE HÉTÉROCYCLIQUES
  申请人：BIOGEN IDEC INC

  公开号：WO2012058645A1

  公开（公告）日：2012-05-03

  The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same. In certain embodiments, the present invention provides pharmaceutical formulations comprising provided compounds. In certain embodiments, the present invention provides a method of decreasing enzymatic activity of a Tec kinase family member. In some embodiments, such methods include contacting a Tec kinase family member with an effective amount of a Tec kinase family member inhibitor. In certain embodiments, the present invention provides a method of treating a disorder responsive to Tec kinase family inhibition in a subject in need thereof.