苯胺,4-乙基-N-羟基-N-亚硝基- | 8067-84-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 中文名称: 苯胺,4-乙基-N-羟基-N-亚硝基-
• 英文名称: Clonidine and chlorthalidone
• 英文别名: 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide;N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
• CAS: 8067-84-3；376634-05-8
• 化学式: C23H20Cl3N5O4S
• 分子量: 568.9
• InChiKey: DLXKTNWIMHQWKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.29
• 重原子数：
  36
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  154
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• SILK RESERVOIRS FOR DRUG DELIVERY
  申请人：Trustees of Tufts College

  公开号：EP2827884A1

  公开（公告）日：2015-01-28
• METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION
  申请人：LeMahieu Edward

  公开号：US20080066741A1

  公开（公告）日：2008-03-20

  Systems and methods for delivery of a drug to the respiratory system of a patient are provided, where the drug is supplied in purified air at a positive pressure relative to atmospheric pressure. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the purified air stream in aerosol, nebulized, or vaporized form.
• US9554989B2
  申请人：——

  公开号：US9554989B2

  公开（公告）日：2017-01-31
• [EN] SILK RESERVOIRS FOR DRUG DELIVERY<br/>[FR] RÉSERVOIRS DE SOIE POUR L'ADMINISTRATION DE MÉDICAMENTS
  申请人：TUFTS COLLEGE

  公开号：WO2013142119A1

  公开（公告）日：2013-09-26

  The present invention is directed to silk-based drug delivery compositions for controlled, sustained delivery of therapeutic agent(s) as well as methods of making and using the same.
• [EN] LASER-ACTUATED THERAPEUTIC NANOPARTICLES<br/>[FR] NANOPARTICULES THÉRAPEUTIQUES ACTIVÉES PAR LASER
  申请人：HARVARD COLLEGE

  公开号：WO2013148158A1

  公开（公告）日：2013-10-03

  The invention provides compositions and methods for laser actuated drug delivery. Compositions comprise serum albumin based particles conjugated with therapeutic agents which cab become bioavailable upon actuation of the particles by light, e.g. low power laser.