N-[(4-叠氮基-2,3,5,6-四氟苯基)甲基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-己酰胺 | 139428-49-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-[(4-叠氮基-2,3,5,6-四氟苯基)甲基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-己酰胺
• 英文名称: N-(4-Azido-2,3,5,6-tetrafluorobenzyl)-6-maleimidohexanamide
• 英文别名: N-[(4-azido-2,3,5,6-tetrafluorophenyl)methyl]-6-(2,5-dioxopyrrol-1-yl)hexanamide
• CAS: 139428-49-2
• 化学式: C17H15F4N5O3
• 分子量: 413.33
• InChiKey: HINBXEWKHNWURU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  29
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  80.8
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Method for producing an arrangement comprising a plurality of layers on the base of semiconductor substrate, multi-layer arrangement, and biosensor
  申请人：Hartig Prosper

  公开号：US20060222565A1

  公开（公告）日：2006-10-05

  A method for producing an arrangement is provided. The arrangement includes a plurality of layers, whereby an organic layer is formed on a surface of a semiconductor substrate, under the influence of irradiated light, by applying a medium containing an organic substance to the surface of the semiconductor substrate, and deposition of the organic substance. A difference in potential is created between the semiconductor substrate and the medium during the deposition of the organic substance, by applying an electrical voltage. The invention also relates to a biosensor comprising an arrangement of a plurality of layers, and to a method for measuring properties of a test constituent using the biosensor. The arrangement of a plurality of layers comprises a semiconductor substrate layer and a layer which is arranged adjacent to the semiconductor substrate layer and contains a biologically active constituent. An interaction section is formed in active communication with the layer containing the biologically active constituent, and a test substance containing a test constituent for interacting with the biologically active constituent can be introduced into said section. Furthermore, said arrangement is provided with at least one connection electrode that is electroconductively connected to the interaction section, and another connection electrode that is electroconductively connected to the semiconductor substrate layer. The at least one connection electrode and the other connection electrode form connection means for coupling to an electric circuit such that an electrical measuring quantity can be obtained between the at least one connection electrode and the other connection electrode, over the arrangement of the plurality of layers and the interaction section, said measuring quantity being able to be modified as a result of the interaction of the test constituent with the biologically active constituent.

  本发明提供了一种生产排列装置的方法。该装置包括多个层，其中，在辐照光的影响下，通过将含有有机物质的介质施加到半导体衬底的表面并沉积有机物质，在半导体衬底的表面形成有机层。在有机物质沉积过程中，通过施加电压，在半导体基板和介质之间产生电位差。本发明还涉及一种生物传感器，包括多个层的排列，以及使用该生物传感器测量测试成分特性的方法。多个层的排列包括一个半导体基底层和一个与半导体基底层相邻并含有生物活性成分的层。在与含有生物活性成分的层之间形成了一个相互作用部分，可将含有与生物活性成分相互作用的测试成分的测试物质引入所述部分。此外，所述装置还设有至少一个与相互作用部分电导连接的连接电极，以及另一个与半导体衬底层电导连接的连接电极。至少一个连接电极和另一个连接电极形成用于与电路耦合的连接装置，从而可以在至少一个连接电极和另一个连接电极之间获得多个层的布置和相互作用部分的电测量量，所述测量量能够因测试成分与生物活性成分的相互作用而改变。