N,N-dimethyl-2-[(4-nitrophenyl)methylideneamino]ethanamine | 1338488-11-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-dimethyl-2-[(4-nitrophenyl)methylideneamino]ethanamine
• CAS: 1338488-11-1
• 化学式: C₁₁H₁₅N₃O₂
• 分子量: 221.259
• InChiKey: XVHOODOENFHFRJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  61.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-甲基苄醇 在 2,2,6,6-四甲基哌啶氧化物 、 2Br^(1-)*C₂₄H₃₆CuN₄O₂⁽²⁺⁾ 、 氧气 作用下， 以 水 、 乙腈 为溶剂， 80.0 ℃ 、200.0 kPa 条件下， 反应 2.0h， 生成 N,N-dimethyl-2-[(4-nitrophenyl)methylideneamino]ethanamine
  参考文献：
  名称：

  Base-free copper-catalyzed aerobic oxidation of benzylic alcohols with N-benzylidene-N,N-dimethylthane-1,2-diamine and TEMPO

  摘要：

  Selective oxidation of alcohols using N-benzylidene-N,N-dimethylthane-1,2-diamine. CuBr2 and TEMPO as the catalytic system was developed. Catalyzed by this simple catalytic system in the absence of any external base, various benzylic alcohols could be oxidized to their corresponding aldehydes with excellent yields in CH3CN/H2O (v/v = 1/1) under 0.2 MPa O-2 at 80 degrees C. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2011.07.019

文献信息

• Base-free copper-catalyzed aerobic oxidation of benzylic alcohols with N-benzylidene-N,N-dimethylthane-1,2-diamine and TEMPO
  作者：Qiufen Wang、Ying Zhang、Gengxiu Zheng、Zhongzhen Tian、Guanyu Yang

  DOI：10.1016/j.catcom.2011.07.019

  日期：2011.10

  Selective oxidation of alcohols using N-benzylidene-N,N-dimethylthane-1,2-diamine. CuBr2 and TEMPO as the catalytic system was developed. Catalyzed by this simple catalytic system in the absence of any external base, various benzylic alcohols could be oxidized to their corresponding aldehydes with excellent yields in CH3CN/H2O (v/v = 1/1) under 0.2 MPa O-2 at 80 degrees C. (C) 2011 Elsevier B.V. All rights reserved.