Base-Catalyzed Transesterification of Thionoesters
作者:Josiah J. Newton、Robert Britton、Chadron M. Friesen
DOI:10.1021/acs.joc.8b02260
日期:2018.10.19
Here we report a convenient synthesis of thionoesters by base-catalyzed transesterification. Benzyl and alkyl thionobenzoates and thionoheterobenzoates were efficiently prepared using various alcohols catalyzed by the corresponding sodium alkoxide. This methodology features a broad substrate scope, good to excellent yields, short reaction times, while simultaneously driving the reaction toward completion