(2S)-1-methoxy-3-(4-methylphenyl)propan-2-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S)-1-methoxy-3-(4-methylphenyl)propan-2-amine
• 化学式: C₁₁H₁₇NO
• 分子量: 179.26
• InChiKey: BBBQZZUGOKEWFT-NSHDSACASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• OX2R COMPOUNDS
  申请人：Board of Regents, The University of Texas System

  公开号：EP3773566A1

  公开（公告）日：2021-02-17
• OX2R Compounds
  申请人：Board of Regents, The University of Texas System

  公开号：US20210107914A1

  公开（公告）日：2021-04-15

  Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.
• [EN] OX2R COMPOUNDS<br/>[FR] COMPOSÉS OX2R
  申请人：UNIV TEXAS

  公开号：WO2019191327A1

  公开（公告）日：2019-10-03

  Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.