Carbamic acid, (3-ethylphenyl)-, ethyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Carbamic acid, (3-ethylphenyl)-, ethyl ester
• 英文别名: ethyl N-(3-ethylphenyl)carbamate
• 化学式: C₁₁H₁₅NO₂
• mdl: MFCD01344028
• 分子量: 193.24
• InChiKey: WPZRRMHARNXPSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease
  申请人：Lycera Corporation

  公开号：US10556898B2

  公开（公告）日：2020-02-11

  The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.

  本发明提供了吲唑基噻二唑胺和相关化合物、药物组合物、抑制Rho相关蛋白激酶的方法，以及使用此类化合物治疗炎症性疾病、免疫性疾病、纤维化疾病和其他疾病的方法。一种示例性的吲唑基噻二唑胺化合物是N-(3-(5-((1H-吲唑-5-基)氨基)-1,2,4-噻二唑-3-基)苯基)-杂芳基甲酰胺化合物。
• INDAZOLYL-1,2,4-THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE
  申请人：Lycera Corporation

  公开号：US20190276447A1

  公开（公告）日：2019-09-12

  The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.
• INK JET INK FOR FORMING AN INFRARED ABSORBING IMAGE, INFRARED ABSORBING IMAGE FORMING METHOD, AND RECORDED MATERIAL
  申请人：FUJIFILM CORPORATION

  公开号：US20220017762A1

  公开（公告）日：2022-01-20

  Provided are an ink jet ink for forming an infrared absorbing image and applications thereof, the ink jet ink including an infrared absorbing material represented by Formula (1), resin particles, a water-soluble organic solvent, a water-soluble organic compound X1, a surfactant, and water. M + represents a proton, a monovalent alkali metal cation, or an organic cation, L 1 represents a methine chain consisting of 5 or 7 methine groups, a methine group at a center of the methine chain has a substituent, R 1 to R 4 each independently represent a hydrogen atom or a substituent, and X represents O, S, or Se.