7,7-Difluoro-2-oxabicyclo<4.1.0>heptane | 131262-44-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: 7,7-Difluoro-2-oxabicyclo<4.1.0>heptane
• 英文别名: 7,7-Difluoro-2-oxabicyclo[4.1.0]heptane；7,7-difluoro-2-oxabicyclo[4.1.0]heptane
• CAS: 131262-44-7
• 化学式: C₆H₈F₂O
• 分子量: 134.126
• InChiKey: ZVQDJKDXPQWJMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.43
• 重原子数：
  9.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  3,4-二氢-2H-吡喃 、 10,10-difluorobicyclo[4.3.1]deca-1,3,5-triene 以94%的产率得到7,7-Difluoro-2-oxabicyclo<4.1.0>heptane
  参考文献：
  名称：

  A photoprecursor for difluorocarbene

  摘要：

  4,4-Difluoropyrazolidine-3,5-dione was synthesized as a precursor for the corresponding pyrazolinedione, envisioned as a photochemical source of difluorocarbene. However, this azo compound proved to be far too unstable. In contrast, 10,10-difluorobicyclo[4.3.1]deca-1,3,5-triene, readily synthesized from indane, was found to be a practical source of difluorocarbene for photochemical as well as thermal cyclopropanation reactions. (C) 2002 Elsevier Science B.V All rights reserved.

  DOI：

  10.1016/s0022-1139(02)00274-9

文献信息

• gem-Difluorocyclopropanes: an improved method for their preparation
  作者：Yves Bessard、Ulrich Müller、Manfred Schlosser

  DOI：10.1016/s0040-4020(01)87828-5

  日期：1990.1
• A photoprecursor for difluorocarbene
  作者：Yigang He、David M. Lemal

  DOI：10.1016/s0022-1139(02)00274-9

  日期：2003.1

  4,4-Difluoropyrazolidine-3,5-dione was synthesized as a precursor for the corresponding pyrazolinedione, envisioned as a photochemical source of difluorocarbene. However, this azo compound proved to be far too unstable. In contrast, 10,10-difluorobicyclo[4.3.1]deca-1,3,5-triene, readily synthesized from indane, was found to be a practical source of difluorocarbene for photochemical as well as thermal cyclopropanation reactions. (C) 2002 Elsevier Science B.V All rights reserved.