2,10-diazaphenanthrene | 229-88-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2,10-diazaphenanthrene
• 英文别名: 2,10-Diazaphenanthren；Benzo[c][1,7]naphthyridine
• CAS: 229-88-9
• 化学式: C₁₂H₈N₂
• 分子量: 180.209
• InChiKey: OZXZPRUEOCYRPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(4-吡啶基)苯甲醛 在 fac-tris(2-phenylpyridinato-N,C2')iridium(III) 、 4-氯苯磺酸 、 4-(aminooxycarbonyl)benzonitrile 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 44.0h， 以55%的产率得到2,10-diazaphenanthrene
  参考文献：
  名称：

  Visible-Light-Promoted and One-Pot Synthesis of Phenanthridines and Quinolines from Aldehydes and O-Acyl Hydroxylamine

  摘要：

  A one-pot synthesis of phenanthridines and quinolines from commercially available or easily prepared aldehydes has been reported. O-(4-Cyanobenzoyl)hydroxylamine was utilized as the nitrogen source to generate O-acyl oximes in situ with aldehydes catalyzed by Bronsted acid. O-Acyl oximes were then subjected to visible light photoredox catalyzed cyclization via iminyl radicals to furnish aza-arenes. A variety of phenanthridines and quinolines have been prepared assisted by Bronsted acid and photocatalyst under visible light at room temperature with satisfactory yields.

  DOI：

  10.1021/acs.orglett.5b01096

文献信息

• [EN] NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME<br/>[FR] NOUVEAUX COMPOSÉS ÉLECTROLUMINESCENTS ORGANIQUES ET DISPOSITIF ÉLECTROLUMINESCENT ORGANIQUE LES UTILISANT
  申请人：ROHM & HAAS ELECT MAT

  公开号：WO2011105700A1

  公开（公告）日：2011-09-01

  Provided are novel organic electroluminescent compounds, and organic electroluminescent devices comprising the same. Since the organic electroluminescent compounds exhibit high luminous efficiency in blue color, and excellent life property of the material, they may be used to manufacture OLEDs having very good operation life.

  提供了新颖的有机电致发光化合物，以及包含这些化合物的有机电致发光器件。由于这些有机电致发光化合物在蓝色方面表现出高发光效率，并且材料具有优秀的寿命特性，因此它们可以用于制造具有非常良好使用寿命的OLED。
• ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER
  申请人：INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY

  公开号：US20190031586A1

  公开（公告）日：2019-01-31

  An organic compound, a three-dimensional organic structure formed by using the organic compound, a separation sieve and an optical layer having the organic structure, and an optical device having the optical layer as an optical amplification layer are provided. The organic structure includes a plurality of organic molecules self-assembled by non-covalent bonding. Each of the unit organic molecules has an aromatic ring, a first pair of substituents being connected to immediately adjacent positions of substitutable positions of the aromatic ring, and a second pair of substituents being connected to immediately adjacent positions of remaining substitutable positions of the aromatic ring. The unit organic molecules are self-assembled by van der Waals interaction, London dispersion interaction or hydrogen bonding between the first and the second pairs of the substituents and by pi-pi interactions between the aromatic rings.

  提供一种有机化合物，通过使用该有机化合物形成的三维有机结构、分离筛和具有该有机结构的光学层，以及具有光学层作为光学放大层的光学器件。该有机结构包括通过非共价键自组装的多个有机分子。每个单元有机分子具有芳香环，第一对取代基连接到芳香环的可取代位置的相邻位置，第二对取代基连接到芳香环的剩余可取代位置的相邻位置。单元有机分子通过范德华力相互作用、伦敦分散相互作用或氢键作用于第一和第二对取代基之间的π-π相互作用而自组装。
• PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER
  申请人：Blend Therapeutics

  公开号：US20140088066A1

  公开（公告）日：2014-03-27

  The present disclosure relates to novel pharmaceutical compositions comprising a nanoparticle associated with, tether to, or encapsulating a platinum-based active pharmaceutical agent. The platinum-based drug is released from the nanoparticles in a controlled fashion. Also contemplated are methods of making the nanoparticles, as well as methods for using them in the treatment or prevention of diseases or conditions. One embodiment relates to phenanthriplatin nanoparticles and methods of using and making the same.

  本公开涉及新型药物组合物，包括与铂类活性药物相关联、连接或封装的纳米颗粒。铂类药物从纳米颗粒中以受控的方式释放。还考虑了制备纳米颗粒的方法，以及在治疗或预防疾病或病症中使用它们的方法。其中一种实施形式涉及苯并芘铂纳米颗粒及其制备和使用方法。
• HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION
  申请人：TOSOH CORPORATION

  公开号：US20160056388A1

  公开（公告）日：2016-02-25

  A novel heterocyclic compound for an organic electroluminescent device excellent in long service life and light-emitting characteristics is provided. A cyclic azine compound has at least one substituent (substituent B) selected from a specific group.

  提供一种新的杂环化合物，用于有机电致发光器件，具有长寿命和发光特性优异。该环状腈化合物至少具有来自特定群组的一个取代基（取代基B）。
• Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof
  申请人：PLACON THERAPEUTICS, INC.

  公开号：US10472380B2

  公开（公告）日：2019-11-12

  The present disclosure relates to novel platinum compositions having a heterocycle ligand and nanoparticles and methods using such compositions, e.g. for treating cancer.

  本公开涉及具有杂环配体的新型铂组合物和纳米颗粒，以及使用此类组合物（如用于治疗癌症）的方法。