1,1-Dipropyl-3-(2-methoxy-5-methylphenyl)urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-Dipropyl-3-(2-methoxy-5-methylphenyl)urea
• 英文别名: 3-(2-methoxy-5-methylphenyl)-1,1-dipropylurea
• 化学式: C₁₅H₂₄N₂O₂
• 分子量: 264.36
• InChiKey: ZWQNNHFRGMKNPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] DRUG COMBINATIONS COMPRISING A DGAT INHIBITOR AND A PPAR-AGONIST<br/>[FR] COMBINAISONS DE MÉDICAMENTS COMPRENANT UN INHIBITEUR DE DGAT ET UN AGONISTE DE PPAR
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2009147170A2

  公开（公告）日：2009-12-10

  The present invention relates to combinations of a DGAT inhibitor and a peroxisome proliferator-activator receptor (PPAR) agonist or a prodrug thereof. The invention further relates to methods for preparing such combinations, pharmaceutical compositions comprising said combinations as well as the use as a medicament of said combinations. The present invention also relates to novel DGAT inhibitors. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use as a medicament of said compounds.