N-methallylpyrrolid-2-one | 52132-71-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: N-methallylpyrrolid-2-one
• 英文别名: 1-(2-methyl-2-propen-1-yl)pyrrolidin-2-one；N-methallylpyrrolidone；1-(2-methylprop-2-enyl)pyrrolidin-2-one
• CAS: 52132-71-5
• 化学式: C₈H₁₃NO
• 分子量: 139.197
• InChiKey: FUNAOUOBENVAFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-methallylpyrrolid-2-one 、 丙酸酐 在 高氯酸 作用下， 以25%的产率得到2-methyl-2-propionylmethyl-5,6-dihydro-7H-pyrrolo<2,1-b>oxazolinium perchlorate
  参考文献：
  名称：

  Acid-catalyzed acetylation of N-methallyl lactam and imide derivatives

  摘要：

  DOI：

  10.1007/bf00475698
• 作为产物：
  描述：

  N-甲基-2-甲基烯丙基胺 在 Rh₂(4(S)-MACIM)4 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 11.5h， 生成 N-methallylpyrrolid-2-one
  参考文献：
  名称：

  Highly Enantioselective Intramolecular Cyclopropanation Reactions of N-Allylic-N-methyldiazoacetamides Catalyzed by Chiral Dirhodium(II) Carboxamidates

  摘要：

  Catalytic diazo decomposition of representative N-allylic-N-methyldiazoacetamides produced the corresponding intramolecular cyclopropanation products in good to excellent yields and with exceptional enantiocontrol. In the simplest case, with N-allyl-N-methyldiazoacetamide, catalysis by dirhodium(II) tetrakis[methyl 2-oxapyrrolidine-5(S)-carboxylate], Rh-2(5(S)-MEPY)(4), achieved the highest yield and enantioselectivity (93% eel. Dirhodium(II) tetrakis[methyl 2-oxo-1-(3-phenylpropanoyl)imidazolidin-4(S)-carboxylate] Rh-2(4S)-MPPIM)(4), was preferred for substituted N-allylic-N-methyldiazoacetamides from which 92-95% ee's were obtained in intramolecular cyclopropanation reactions (88-95% yields), even when the catalyst was employed in only 0.1 mol %, Competition with intramolecular dipolar cycloaddition was minimized with the use of N-methyldiazoacetamides relative to N-tert-butyldiazoacetamides.

  DOI：

  10.1021/jo9519219

文献信息

• Glucosamine-peptide derivatives and their pharmaceutical compositions
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0002677A1

  公开（公告）日：1979-07-11

  Compounds, of the following formula and their physiologically acceptable salts: where: R is hydrogen or a group of the formule R'CO-(wherein R' is an acyclic hydrocarbon group which may be substituted by a cyclic hydrocarbon group -2.3.2,3-dimethoxty-5-methyl-1,4-benzoquinon-6-YI at its ω-position) or a group of the formula They have an immunostimulatory activity.

  下式化合物及其生理上可接受的盐类： 其中 R 是氢或形式为 R'CO-(wherein R'为无环烃基，可在ω位被环烃基-2.3.2,3-二甲氧基-5-甲基-1,4-苯醌-6-YI 取代）或式中的基团 它们具有免疫刺激活性。
• Ink composition for 3D printing support and 3D printing manufacturing method using the same
  申请人：LG Chem, Ltd.

  公开号：US10954404B2

  公开（公告）日：2021-03-23

  The present invention relates to an ink composition for a 3D printing support, comprising an amine-containing monomer and a curing agent. According to the present invention, an ink composition for a 3D printing support, which retains an excellent jetting property, is well dissolved in water after being photo-cured to be easily removed, and has less curing contraction and excellent storage stability, can be provided.

  本发明涉及一种用于 3D 打印支架的油墨组合物，由含胺单体和固化剂组成。根据本发明，可提供一种用于 3D 打印支架的油墨组合物，该组合物可保持优异的喷射性能，在光固化后可很好地溶解于水以便于去除，并且具有较小的固化收缩和优异的储存稳定性。
• VOSHCHULA, V. N.;TOLKUNOV, S. V.;ZUBRITSKIJ, M. YU.;DULENKO, V. I., XIMIYA GETEROTSIKL. SOED.,(1988) N 10, S. 1414-1419
  作者：VOSHCHULA, V. N.、TOLKUNOV, S. V.、ZUBRITSKIJ, M. YU.、DULENKO, V. I.

  DOI：——

  日期：——
• Anti-fouling agent
  申请人：Nitto Kasei Co., Ltd.

  公开号：EP0091039B1

  公开（公告）日：1986-10-01
• INK COMPOSITION FOR 3D PRINTING SUPPORT AND 3D PRINTING MANUFACTURING METHOD USING THE SAME
  申请人：LG Chem, Ltd.

  公开号：US20180215937A1

  公开（公告）日：2018-08-02

  The present invention relates to an ink composition for a 3D printing support, comprising an amine-containing monomer and a curing agent. According to the present invention, an ink composition for a 3D printing support, which retains an excellent jetting property, is well dissolved in water after being photo-cured to be easily removed, and has less curing contraction and excellent storage stability, can be provided.