1-Cyclohexyl-3-(3,4-dimethylphenyl)urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Cyclohexyl-3-(3,4-dimethylphenyl)urea
• 化学式: C₁₅H₂₂N₂O
• mdl: MFCD00088118
• 分子量: 246.35
• InChiKey: JTALIXBIKQUNSF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.533
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• [EN] METHODS FOR TREATING SYNOVIAL SARCOMA<br/>[FR] MÉTHODES DE TRAITEMENT DU SARCOME SYNOVIAL
  申请人：UNIV LELAND STANFORD JUNIOR

  公开号：WO2017062510A1

  公开（公告）日：2017-04-13

  Methods useful in the treatment of synovial sarcoma are provided. The methods comprise administering to a subject suffering from synovial sarcoma a compound as disclosed herein. Also provided are novel compounds having therapeutic effects on subjects suffering from synovial sarcoma and pharmaceutical compositions comprising the compounds. The compounds were identified by screening for agents that promote the assembly of wild-type BAF (also called mSWI/SNF) complexes in modified SS cells.