3-{2-[2,4-bis-(1,1-dimethyl-propyl)-phenoxy]-acetylamino}-N-[5-oxo-1-(2,4,6-trichloro-phenyl)-2,5-dihydro-1H-pyrazol-3-yl]-benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-{2-[2,4-bis-(1,1-dimethyl-propyl)-phenoxy]-acetylamino}-N-[5-oxo-1-(2,4,6-trichloro-phenyl)-2,5-dihydro-1H-pyrazol-3-yl]-benzamide
• 英文别名: 3-[2-(2,4-di-tert-pentyl-phenoxy)-acetylamino]-benzoic acid-[5-oxo-1-(2,4,6-trichloro-phenyl)-2,5-dihydro-1H-pyrazol-3-ylamide]；3-[2-(2,4-Di-tert-pentyl-phenoxy)-acetylamino]-benzoesaeure-[5-oxo-1-(2,4,6-trichlor-phenyl)-2,5-dihydro-1H-pyrazol-3-ylamid]；3-({[2,4-bis(2-methylbutan-2-yl)phenoxy]acetyl}amino)-N-[5-hydroxy-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]benzamide；3-[[2-[2,4-bis(2-methylbutan-2-yl)phenoxy]acetyl]amino]-N-[3-oxo-2-(2,4,6-trichlorophenyl)-1H-pyrazol-5-yl]benzamide
• 化学式: C₃₄H₃₇Cl₃N₄O₄
• 分子量: 672.051
• InChiKey: NFQCZOCWVMXBJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.7
• 重原子数：
  45
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  99.8
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-{2-[2,4-bis-(1,1-dimethyl-propyl)-phenoxy]-acetylamino}-N-[5-oxo-1-(2,4,6-trichloro-phenyl)-2,5-dihydro-1H-pyrazol-3-yl]-benzamide 生成 3-[2-(2,4-di-tert-pentyl-phenoxy)-acetylamino]-benzoic acid-[5-oxo-1-(2,4,6-trichloro-phenyl)-4-xanthen-9-yl-2,5-dihydro-1H-pyrazol-3-ylamide]
  参考文献：
  名称：

  Pyrazolone couplers for color photography

  摘要：

  吡唑酮衍生物是通过将一或两分子比例的吡唑酮与黄橙酮、烯醛或三酮水合物缩合而制备的。在乙酸中回流1-苯基-3-(a-苯丁酰氨基)-4-黄橙酮-5-吡唑酮和黄橙酚可制备1-苯基-3-(a-苯丁酰氨基)-4-黄橙酮基-5-吡唑酮。类似地制备了1-(21:41:61-三氯苯基)-3-[311-(2111:4111-二-叔丁基苯氧乙酰氨基)-苯甲酰氨基]-4-黄橙酮基-5-吡唑酮、4:41-三酮水合物-双-1-(21:41:61-三氯苯基)-3-[311-(2111:4111-二-叔丁基苯氧乙酰氨基)-苯甲酰氨基]-5-吡唑酮和黄橙酮-双-1-(对-叔丁基苯氧基)-苯基-3-间-(对-叔丁基苯氧基苯甲酰氨基)-5-吡唑酮。通过在吡啶中回流1-(对-叔丁基苯氧基)-苯基-3-间-(对-叔丁基苯氧基丙酰氨基)-5-吡唑酮和黄橙酮单水合物可制备4:41-黄橙酮-双-1-(对-叔丁基苯氧基)-苯基-3-间-(对-叔丁基苯氧基丙酰氨基)-5-吡唑酮。通过将黄橙酮单水合物逐渐加入到蒸馏水中1-苯基-3-甲基-5-吡唑酮的悬浮液中可制备4-(4-羟基黄橙酮)-1-苯基-3-甲基-5-吡唑酮。类似地制备了4-(4-羟基)-三酮水合物-1-苯基-3-甲基-5-吡唑酮。参考规格524,154、524,554、524,555、541,589、[均在XX组中]和680,488。

  公开号：

  US02632702A1

文献信息

• Bis-pyrazolone for color photography
  申请人：EASTMAN KODAK CO

  公开号：US02706683A1

  公开（公告）日：1955-04-19

  a - 41 - 11 - (211 : 411 : 611 - Trichlorophenyl) - 31 - [3111 - (2111 : 4111 - di - tert. - amylphenoxyacetamido) - benzamido] - 51 - pyrazolonyl}} - 1 - phenyl - 3 - methyl - 4 - (p - methoxybenzyl) - 5 - pyrazolone is prepared by refluxing together 1-phenyl-3-methyl-4-(41-methoxybenzylidene) - 5 - pyrazolone and 1-(21 : 41 : 61 - trichlorophenyl) - 3 - [311\h - (2111 : 4111 - di - tert. - amylphenoxyacetamido) - benzamido] - 5 - pyrazolone in acetic acid containing sodium acetate. a -41 - (11 - Benzthiazolyl) - 31 - [(311 - tert. - amylphenoxy) - benzamido] - 51-pyrazolonyl}} - 1 - phenyl - 3 - amino - 4 - (p-methoxybenzyl) - 5 - pyrazolone, a - 41 - [11-phenyl - 31 - a - phenylbutyramido - 51 - pyrazolonyl]} - 1 - [411 - (4111 - tert. - butylphenoxy)-phenyl] - 3 - [41111 - (41111 - tert. - butylphenoxy)-phenyl] - carbamyl - 4 - (p - methoxybenzyl) - 5-pyrazolone, and a - 1 - (21 - benzthiazolyl) - 3-d - [41 - (311 - p - tert. - amylphenoxy) - benzamido phenyl] - valeramido - 5 - pyrazolonyl} - 1-phenyl - 3 - a - phenylbutyrylamino - 4 - p-methoxybenzyl - 5 - pyrazolone are similarly prepared. 1 - Phenyl - 3 - methyl - 4 - (41 - methoxybenzylidene) - 5 - pyrazolone is prepared by heating together 1 - phenyl - 3 - methyl - 5-pyrazolone and p-methoxybenzaldehyde in glacial acetic acid. 1-Benzthiazolyl-3-[31-(tert.-amylphenoxy) - benzamido] - 4 - p - methoxybenzylidene - 5 - pyrazolone and 1 - phenyl - 3-a - phenylbutyramido - 4 - anisal - 5 - pyrazolone are similarly prepared. 1 - [41 - [411 - Tert. - Butylphenoxy) - phenyl]-3 - [4111 - (41111 - tert. - butylphenoxy) - phenyl]-carbamyl - 5 - pyrazolone is prepared by acylating 4-tert.-butylphenoxyaniline with 1-(41 - tert. - butylphenoxy) - phenyl - 3 - carboxy-5-pyrazolone. 1 - (21 - Benzthiazolyl) - 3 - d - [41 - (311 - p-tert. - amylphenoxy) - benzamido] - phenylvaleramido) - 5 - pyrazolone is prepared by acylating 1 - (21 - benzthiazolyl) - 3 - (d - 41-aminophenylvaleramido) - 5 - pyrazolone with 4 - (31 - p - tert.-amylphenoxy) - benzoyl chloride. Specifications 524,154, 524,555, 541,589, [all in Group XX], 599,919 and 680,488 are referred to.

  将1-苯基-3-甲基-4-(对-甲氧基苄基)-5-吡唑酮与1-(2,4,6-三氯苯基)-3-[3-(2,4-二叔丁基苯氧基)苯基氨基]-5-吡唑酮在含有乙酸钠的冰醋酸中回流，制备出a-41-11-(苯并噻唑基)-31-[(3-叔丁基苯氧基)苯基氨基]-51-吡唑酮基}}-1-苯基-3-氨基-4-(对-甲氧基苄基)-5-吡唑酮，a-41-[11-苯基-31-a-苯基丁酰氨基-51-吡唑酮基]}-1-[4-(4-叔丁基苯氧基)苯基]-3-[4-(4-叔丁基苯氧基)苯基]羰基-4-(对-甲氧基苄基)-5-吡唑酮，以及a-1-(苯并噻唑基)-3-d-[41-(3-叔丁基苯氧基)苯基氨基苯基]戊酰氨基-5-吡唑酮}-1-苯基-3-a-苯基丁酰氨基-4-对-甲氧基苄基-5-吡唑酮同样制备。1-苯基-3-甲基-4-(对-甲氧基苄基)-5-吡唑酮通过在冰醋酸中加热1-苯基-3-甲基-5-吡唑酮和对-甲氧基苯甲醛制备。1-苯并噻唑基-3-[3-(叔丁基苯氧基)苯基氨基]-4-对-甲氧基苄基-5-吡唑酮和1-苯基-3-a-苯基丁酰氨基-4-苯甲醛-5-吡唑酮同样制备。1-[4-(叔丁基苯氧基)苯基]-3-[4-(4-叔丁基苯氧基)苯基]羰基-5-吡唑酮通过用1-(4-叔丁基苯氧基)苯基-3-羧基-5-吡唑酮酰化4-叔丁基苯氧基苯胺制备。1-(苯并噻唑基)-3-d-[4-(3-叔丁基苯氧基)苯基氨基]-苯基戊酰氨基-5-吡唑酮通过用1-(苯并噻唑基)-3-(d-4-氨基苯基戊酰氨基)-5-吡唑酮酰化4-(3-叔丁基苯氧基)苯甲酰氯制备。规格524,154, 524,555, 541,589，[均在XX组中]，599,919和680,488被引用。
• Photographic couplers with N-heterocyclic development inhibiting
  申请人：Fuji Photo Film Co., Ltd.

  公开号：US04086094A1

  公开（公告）日：1978-04-25

  A light-sensitive silver halide photographic material comprising a support having thereon at least one hydrophilic colloid layer which contains a color-forming coupler having a nitrogen-containing residue releasable on reaction of the coupler with an oxidation product of a color developing agent and which contains a thiocarbonyl group (S.dbd.C<), a selenocarbonyl group (Se.dbd.C<) or a telluriumcarbonyl group (Te.dbd.C<), the nitrogen atom of the nitrogen-containing residue being attached to the carbon atom in the coupling position of the coupler.

  一种光敏银卤片材，包括有至少一层亲水胶体层的支撑体，所述亲水胶体层含有一种含有氮含基的发色偶合剂，该发色偶合剂在与发色剂的氧化产物反应时释放出来，且含有硫代羰基（S.dbd.C<）、硒代羰基（Se.dbd.C<）或碲代羰基（Te.dbd.C<），所述氮含基的氮原子与偶合剂的偶合位置的碳原子相连。
• Light-sensitive silver halide color photographic material
  申请人：KONICA CORPORATION

  公开号：EP0087931A1

  公开（公告）日：1983-09-07

  Disclosed is a light-sensitive silver halide color photographic material, having a blue sensitive silver halide emulsion layer, a green sensitive silver halide emulsion and a red sensitive silver halide emulsion on a support; which comprises said red sensitive silver halide emulsion containing at least one kind of the compounds represented by the formula [I] shown below, and further the content of the silver halide contained in all of the aforesaid light-sensitive silver halide emulsion layer being 7.5 g/m2 or more as calculated on silver, and the content of the silver halide contained in said red sensitive silver halide emulsion being 3.5 g/m2 or more as calculated on silver: Formula [I]: wherein, X, R1 and R2 are as defined in the specification.

  本发明公开了一种感光型卤化银彩色感光材料，它具有蓝色感光型卤化银乳剂层、绿色感光型卤化银乳剂层和红色感光型卤化银乳剂层；其中，所述红色感光型卤化银乳剂层含有至少一种下式[I]所代表的化合物，并且上述所有感光型卤化银乳剂层所含卤化银的含量以银为单位计算为 7.5 g/m2 或以上，所述红色感光型卤化银乳剂层所含卤化银的含量以银为单位计算为 3.5 g/m2 或以上：式[I]：其中，X、R1 和 R2 如说明书中所定义。
• Silver halide photographic light sensitive material
  申请人：KONICA CORPORATION

  公开号：EP0109831A2

  公开（公告）日：1984-05-30

  A silver halide photographic light-sensitive material is described which comprises a support having thereon a plurality of silver halide emulsion layers which have different speeds but have sensitivities in the same spectral region, and at least one light-sensitive layer comprising a nondiffusible coupler capable of forming nondiffusible dye by reaction with an oxidization product of a color developing agent, wherein the silver halide emulsion layer having the highest speed among said plurality of silver halide emulsion layers contains a nondiffusible coupler capable of producing a movable dye by reaction with an oxidization product of a color developing agent, and a silver halide emulsion layer having a lower speed than that of said layer having the highest speed, which contains a nondiffusible compound capable of releasing a development inhibitor by reaction with an oxidization product of a color developing agent.

  本发明描述了一种卤化银感光摄影材料，该材料包括一个支撑体，支撑体上有多个卤化银乳剂层，这些层的速度不同，但在同一光谱区域具有不同的感光度；以及至少一个感光层，该感光层包含一个不可扩散耦合剂，该耦合剂能够通过与显色剂的氧化产物反应形成不可扩散染料、其中，在所述多个卤化银乳剂层中，速度最快的卤化银乳剂层含有能与显色剂的氧化产物反应生成可动染料的不可扩散耦合剂，以及速度低于速度最快的卤化银乳剂层，该层含有能与显色剂的氧化产物反应释放显影抑制剂的不可扩散化合物。
• Process for forming direct positive images, direct positive silver halide elements, compositions and compounds as characteristic feature of such processes and elements
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0168730A2

  公开（公告）日：1986-01-22

  Direct positive photographic elements are disclosed employing internal latent image silver halide emulsions associated with developer autoxidation promoter agents constituted by 5 or 6 membered nucleus-containing heterocyclic compounds comprising an azomethine group, whose methine group is substituted with a 5-amino-1,2,4-triazolyl group, and/or copper complex compounds thereof. Preferably said direct positive photographic elements are multilayer elements comprising internal latent image type type silver halide emulsion layers sensitized to different regions of the visible light and associated with image-dye providing compounds (photographic color couplers).

  本发明公开了直接正像照相元件，该元件采用了与显影剂自氧化促进剂有关的内潜像型卤化银乳剂，该促进剂由包含偶氮甲基的 5 或 6 个含核杂环化合物构成，其甲基被 5-氨基-1,2,4-三唑基取代，和/或其铜络合物。 上述直接正像感光元件最好是多层元件，包括对可见光的不同区域感光的内部潜像型卤化银乳剂层，并与提供图像染料的化合物（感光颜色耦合剂）相关联。