1,4-Bis-tert-butyl-tetrafluorbenzol | 54111-17-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,4-Bis-tert-butyl-tetrafluorbenzol
• 英文别名: 1,4-DI-Tert-butyl-2,3,5,6-tetrafluorobenzene；1,4-ditert-butyl-2,3,5,6-tetrafluorobenzene
• CAS: 54111-17-0
• 化学式: C₁₄H₁₈F₄
• 分子量: 262.291
• InChiKey: SOUQAPNRIRYTOB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：Universal Display Corporation

  公开号：US20190088889A1

  公开（公告）日：2019-03-21

  The present invention includes novel heteroleptic/homoleptic iridium complexes containing two tridentate ligands, where at least one of the tridentate ligands comprises of pyridinium-derived N-heterocyclic carbene. The compounds of the present invention may be useful for organic electroluminescent devices.

  本发明包括含有两个三齿配体的新型异配/同配铱配合物，其中至少一个三齿配体由吡啶鎓衍生的N-杂环卡宾组成。本发明的化合物可能对有机电致发光设备有用。
• Organic Electroluminescent Materials and Devices
  申请人：Universal Display Corporation

  公开号：US20200274081A1

  公开（公告）日：2020-08-27

  A compound of Formula I wherein: ring B is a 5-membered heterocyclic ring, or a 6-membered carbocyclic ring; each of X 1 and X 2 is independently C, CR, or N, with at least one of them being C; each of X 3 -X 11 is independently C, CR, or N, with at least one of them being N, and two adjacent of X 3 -X 7 are carbon-fused to the shown moiety through the linkage indicated by the two squiggly lines; Y is selected from the group consisting of O, S, Se, NR′, CR′R″, and SiR′R″; each of R A and R B independently represents zero, mono, or up to a maximum allowed substitution to its associated ring; each of R, R′, R″, R A , and R B is independently a hydrogen or a substituent selected from the group consisting of —SiR 1 R 2 R 3 or —GeR 1 R 2 R 3 , deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, boryl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof, with at least one of R A or R B comprising —SiR 1 R 2 R 3 or —GeR 1 R 2 R 3 ; each of R 1 , R 2 , and R 3 is independently selected from the group consisting of alkyl, aryl group, heteroaryl group, and combinations thereof; and any two substituents are optionally joined or fused to form a ring where chemically feasible.

  根据公式I的化合物 其中： 环B是5元的杂环，或者是6元的碳环； X1和X2各自独立为C、CR或N，其中至少有一个是C； X3-X11各自独立为C、CR或N，其中至少有一个是N，并且X3-X7的两个相邻碳与所示基团通过波浪线指示的连接方式碳融合； Y选自由O、S、Se、NR'、CR'R"和SiR'R"组成的组； RA和RB各自独立代表其相关环允许的最大取代数，零、单或至多； R、R'、R"、RA和RB各自独立为氢或选自—SiR1R2R3或—GeR1R2R3，氘，卤素，烷基，环烷基，杂烷基，杂环烷基，芳烷基，烷氧基，芳氧基，氨基，硅基，硼基，烯基，环烯基，杂烯基，炔基，芳基，杂芳基，酰基，羧酸，醚，酯，腈，异腈，硫anyl，亚磺酰基，磺酰基，磷基和它们的组合的取代基，其中至少一个RA或RB包含—SiR1R2R3或—GeR1R2R3； R1、R2和R3各自独立选自烷基，芳基组，杂芳基组和它们的组合；并且 任意两个取代基可选择性连接或融合成环，在化学上可行的话。
• ORGANIC HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES
  申请人：UNIVERSAL DISPLAY CORPORATION

  公开号：US20190109286A1

  公开（公告）日：2019-04-11

  A compound of Formula I is disclosed where R A , R B , R C , and R D each independently represent mono to a maximum possible number of substitutions, or no substitution; where two of X 1 to X 4 are carbon, and the other two are nitrogen; where L is an organic linker, where R, R A , R B , R C , and R D are each independently a hydrogen or a substituent selected from the group consisting of deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof; where R D does not comprise a dibenzothiophene group; and where any adjacent substituents are optionally joined or fused into a ring.

  公开了一种Formula I的化合物，其中RA、RB、RC和RD分别独立地表示单个到最大可能数量的取代基，或者无取代基；其中X1到X4中的两个是碳，另外两个是氮；其中L是有机连接剂，其中R、RA、RB、RC和RD分别独立地是氢或从氘、卤素、烷基、环烷基、杂原子烷基、杂环烷基、芳基烷基、烷氧基、芳氧基、氨基、硅基、烯基、环烯基、杂原子烯基、炔基、芳基、杂芳基、酰基、羧酸、醚、酯、腈、异腈、硫基、亚硫基、砜基、磷基及其组合中选择的取代基；其中RD不包括二苯并噻吩基团；并且任何相邻的取代基可以选择性地连接或融合成环。
• Radiolabelling Method Using Polymers
  申请人：Gacek Michel

  公开号：US20080305042A1

  公开（公告）日：2008-12-11

  The present invention provides a method for the preparation of radioisotopically-labelled imaging agent compositions. The method uses precursors which are bound to soluble polymers, so that the radiolabelling reaction is carried out in solution. Also described are radiopharmaceutical compositions, automated versions of the radiolabelling method and disposable cassettes for use in the automated method.

  本发明提供了一种制备放射性同位素标记成像剂组合物的方法。该方法使用与可溶性聚合物结合的前体物质，使放射标记反应在溶液中进行。还描述了放射性药物组合物、放射标记方法的自动化版本以及用于自动化方法的一次性盒子。
• Solid-Phase Preparation of [18F]Fluorohaloalkanes
  申请人：Brady Frank

  公开号：US20070202039A1

  公开（公告）日：2007-08-30

  The invention relates to a process for the production of an [ 18 F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO 2 —O—(CH 2 ) n X  (I) wherein n is an integer of from 1 to 7 and X is chloro, bromo or iodo; with 18 F − to produce the [ 18 F]fluorohaloalkane of formula (II) 18 F—(CH 2 ) n —X  (II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18 F − , for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.

  本发明涉及一种制备[18F]氟卤代烷的方法，包括将式(I)的固相支持前体进行处理：SOLID SUPPORT-LINKER-SO2—O—(CH2)nX  (I)，其中n为1至7的整数，X为氯、溴或碘；使用18F−产生式(II)的[18F]氟卤代烷：18F—( )n—X  (II)，其中n和X如式(I)中所定义，可选择性地进行以下步骤：(i)去除多余的18F−，例如通过离子交换色谱法；和/或(ii)去除有机溶剂。